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Trial · NCT06083948

Vasopressor Impact on Brain Circulation, Organ Blood Flow and Tissue Oxygenation During Anesthesia

NCT06083948, Phase 2, Phase 3, Recruiting, University of Aarhus

3 sourcestrials-2026-11-12-0.5.0

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ConductScience Library. Vasopressor Impact on Brain Circulation, Organ Blood Flow and Tissue Oxygenation During Anesthesia. Trials, record NCT06083948. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT06083948

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Trial

As registered on ClinicalTrials.gov, in the graph's capture of the registry.

Title
Vasopressor Impact on Brain Circulation, Organ Blood Flow and Tissue Oxygenation During Anesthesia
NCT number
NCT06083948
Status
Recruiting
Phases
Phase 2, Phase 3
Enrollment
32 participants, estimated
Lead sponsor
University of Aarhus
Conditions
Hypotension
Interventions
Noradrenalin, Phenylephrine
First posted
2023-10-16
Last updated
2026-03-19

Source ClinicalTrials.gov

Registered outcomes8

Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.

ListOutcomeTime frameDescription
PrimaryCerebral blood flowUp to 3 hours (measured on the day of surgery prior to the surgical procedure)Blood flow measured in milliliters per minute through selected regions of the brain as determined by Positron Emission Tomography
SecondaryCerebral metabolic rate of oxygenUp to 4 hours (measured on the day of surgery prior to the surgical procedure)Cerebral oxygen consumption in selected regions of the brain as determined by Positron Emission Tomography
SecondaryBlood flow through body organs in milliliters per minute as determined by Positron Emission TomographyUp to 4 hours (measured on the day of surgery prior to the surgical procedure)Blood flow in various body organs supplied by the systemic circulation
SecondaryBlood pumped out by the heart per minute (cardiac output)Up to one dayCardiac output as determined by Positron Emission Tomography and/or by beat-to-beat determination by analysis of the arterial blood pressure waveform
SecondaryIschemic lesionsUp to 3 daysIschemic lesions possibly associated with vasopressor use as detected on the postoperative MRI examination
SecondaryCerebral tissue oxygen saturationUp to one dayCerebral tissue oxygen saturation as measured with near infrared spectroscopy (NIRS)
SecondaryBispectral Index (BIS)Up to one dayDepth of anesthesia as measured by BIS
SecondaryOrgan metabolic rate of OxygenUp to 3 hours (measured on the day of surgery prior to the surgical procedure)Oxygen consumption in various organs as measured by Positron Emission Tomography

Outcomes0

Each outcome the trial posted results for, in ClinicalTrials.gov's words.

None in this release.

Results by group0

Each measurement the trial posted, group by group, in the words and numbers it posted.

None in this release.

Participant flow0

How many started, completed or left each group, period by period.

None in this release.

Adverse events0

Each adverse event the trial posted, group by group: the participants affected out of those at risk.

None in this release.

Adverse event totals0

The totals the trial posted for each group.

None in this release.

Papers1

The papers the trial lists on ClinicalTrials.gov.

PMIDListed as
40132839DERIVED

Source PubMed

Grants0

The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.

None in this release.

Trial comparisons0

Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.

None in this release.

Tests0

The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.

None in this release.

Data dates

The day each source was copied for this release.

ClinicalTrials.gov
2026-11-12
ClinicalTrials.gov
Results, from AACT
2026-03-23
AACT
NIH grant links
2026-11-13
NIH RePORTER

Sources 3

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ClinicalTrials.govNo license stated
  • NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ClinicalTrials.govnone stated
  • NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this trial from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/trials/v1/NCT06083948

GET https://conductscience.org/api/trials/v1/NCT06083948/registered