Trial · NCT06113055
Hereditary Sensory Neuropathy Serine Trial
NCT06113055, Phase 2, Unknown, University College, London
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. Hereditary Sensory Neuropathy Serine Trial. Trials, record NCT06113055. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT06113055
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- Hereditary Sensory Neuropathy Serine Trial
- NCT number
- NCT06113055
- Status
- Unknown
- Phases
- Phase 2
- Enrollment
- 50 participants, estimated
- Lead sponsor
- University College, London
- Conditions
- Hereditary Sensory Neuropathy Type I
- Interventions
- L-serine, Placebo
- First posted
- 2023-11-02
- Last updated
- 2023-11-02
Source ClinicalTrials.gov
Registered outcomes9
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | MRC Muscle Fat Fraction protocol | 12 months | The primary outcome measure will be the mean difference in change from baseline lower limb muscle fat fraction at the severity appropriate anatomical level measured by MRI over 12 months between L-serine treated and placebo treated groups. The primary outcome has units of percentage fat fraction (%FF) and is a continuous variable. |
| Secondary | Secondary outcome measures | 12 months | Charcot Marie Tooth Neuropathy Score (CMTNS) v2 and v2-Rasch |
| Secondary | Secondary/Exploratory outcome measures | 12 months | plasma neurofilament light chain levels |
| Secondary | Secondary/Exploratory outcome measures | 12 months | plasma deoxysphingolipid levels |
| Secondary | Secondary/Exploratory outcome measures | 12 months | thigh intraepidermal nerve fibre density |
| Secondary | Secondary outcome measures | 12 months | Charcot Marie Tooth Health Index Quality of Life Score |
| Secondary | Secondary outcome measure | 12 months | Neuropathic Pain Diagnostic Questionnaire |
| Secondary | Secondary outcome measure | 12 months | Neuropathic Pain Symptom Inventory |
| Secondary | Secondary outcome measure | 12 months | Brief Pain Inventory |
Source ClinicalTrials.gov
Outcomes0
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
None in this release.
Results by group0
Each measurement the trial posted, group by group, in the words and numbers it posted.
None in this release.
Participant flow0
How many started, completed or left each group, period by period.
None in this release.
Adverse events0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
None in this release.
Adverse event totals0
The totals the trial posted for each group.
None in this release.
Papers1
The papers the trial lists on ClinicalTrials.gov.
| PMID | Listed as |
|---|---|
| 42231561 | DERIVED |
Source PubMed
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
None in this release.
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT06113055
GET https://conductscience.org/api/trials/v1/NCT06113055/registered