Water-based Activity to Enhance Recovery in Long COVID-19
NCT06142253, Not applicable, Recruiting, VA Office of Research and Development
Trial 10
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
| Field | Value | Source |
|---|---|---|
| Title | Water-based Activity to Enhance Recovery in Long COVID-19 | ClinicalTrials.gov |
| NCT number | NCT06142253 | ClinicalTrials.gov |
| Status | Recruiting | ClinicalTrials.gov |
| Phases | Not applicable | ClinicalTrials.gov |
| Enrollment | 50 participants, estimated | ClinicalTrials.gov |
| Lead sponsor | VA Office of Research and Development | ClinicalTrials.gov |
| Conditions | Long COVID | ClinicalTrials.gov |
| Interventions | WATER+CT, Usual Care | ClinicalTrials.gov |
| First posted | 2023-11-21 | ClinicalTrials.gov |
| Last updated | 2026-06-18 | ClinicalTrials.gov |
Registered outcomes 14
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description | Source |
|---|---|---|---|---|
| Primary | Feasibility of Intervention Measure | At the end of study completion, an average of 8 months | The FIM is a brief measure of the feasibility of an intervention. | ClinicalTrials.gov |
| Secondary | Acceptability of Intervention Measure | At the end of study completion, an average of 8 months | The AIM is a brief measure that assesses the acceptability of an intervention. | ClinicalTrials.gov |
| Secondary | Change in Fatigue Severity Scale | Through study completion, an average of 8 months | The Fatigue Severity Scale (FSS) is a method of evaluating the impact of fatigue on a person. The FSS is a short questionnaire that requires a person to rate his/her level of fatigue using a scale of 1 (completely disagree) to 7 (completely agree). Scores range from 9 to 63 with higher scores indicating greater fatigue severity. | ClinicalTrials.gov |
| Secondary | Change in Mental Fatigue Scale | Through study completion, an average of 8 months | The Mental Fatigue Scale (MFS) is self-report scale that includes 15 questions which assess mental fatigue. Items are rated on a scale that ranges from 0 (normal function) to 3 (serious problems). Higher scores indicate greater symptom severity. | ClinicalTrials.gov |
| Secondary | Change in Digit Span | Through study completion, an average of 8 months | The Digit Span subt-test of the WAIS-IV assesses attention and working memory. | ClinicalTrials.gov |
| Secondary | Change in Digit Symbol Substitution Test | Through study completion, an average of 8 months | The Digit Symbol Substitution Test from the WAIS-III assesses attention, processing speed and executive function. | ClinicalTrials.gov |
| Secondary | Change in Stroop Color Word Test | Through study completion, an average of 8 months | The Stroop Color Word test assesses selection attention, cognitive inhibition, and processing speed. | ClinicalTrials.gov |
| Secondary | Change in Rey Auditory Verbal Learning Test | Through study completion, an average of 8 months | The Rey Auditory Verbal Learning Test; (RAVLT) assesses learning and memory. | ClinicalTrials.gov |
| Secondary | Change in NIH Toolbox Cognitive Battery | Through study completion, an average of 8 months | The NIH Toolbox is a computerized battery of test that assesses neuropsychological function. | ClinicalTrials.gov |
| Secondary | Change in Hospital Anxiety and Depression Scale | Through study completion, an average of 8 months | The Hospital Anxiety and Depression Scale (HADS) is a 14-time self-rating scale to assess psychological distress in non-psychiatric patients. Items are rated on a 4-point Likert scale (range 0-3). The total score ranges from 0 to 42 with higher indicating greater severity. | ClinicalTrials.gov |
| Secondary | Change in World Health Organization Disability assessment scale 2.0 | Through study completion, an average of 8 months | The World Health Organization Disability assessment scale 2.0 (WHODAS 2.0) assesses multiple domains of function including: cognition, mobility, self-care, getting along, life activities (household and work) and participation. | ClinicalTrials.gov |
| Secondary | Change in Canadian Occupation Performance Measure | Through study completion, an average of 8 months | The Canadian Occupation Performance Measure (COPM) assesses an individual's perceived occupational performance in the areas of self-care, productivity, and leisure. | ClinicalTrials.gov |
| Secondary | Change in Blood labs | Through study completion, an average of 8 months | Standard blood labs include C-Reactive Protein, Interleukin-6, metabolic panel, and lipid panels | ClinicalTrials.gov |
| Secondary | Genetic Testing | Baseline | Genetic testing includes assessment of APOE and BDNF genotypes. | ClinicalTrials.gov |
Outcomes 0
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
| Type | Outcome | Time frame | Population | Units | Measured as | Source |
|---|
Results by group 0
Each measurement the trial posted, group by group, in the words and numbers it posted.
| Outcome | Group | Category | Value | Spread | Units | Source |
|---|
Participant flow 0
How many started, completed or left each group, period by period.
| Period | Milestone | Group | Participants | Units counted | Source |
|---|
Adverse events 0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
| Type | Event | Organ system | Group | Affected | At risk | Events | Source |
|---|
Adverse event totals 0
The totals the trial posted for each group.
| Total | Group | Affected | At risk | Source |
|---|
Papers 0
The papers the trial lists on ClinicalTrials.gov.
| PMID | Listed as | Source |
|---|
Grants 0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
| Project | Title | Principal investigators | Organization | Funder | Fiscal years | Source |
|---|
Trial comparisons 0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
| Comparison | Source |
|---|
Tests 4
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
| Test | Named as | Source |
|---|---|---|
| Digit Span Test | Secondary outcome | ConductCognition |
| Stroop Color-Word Test | Secondary outcome | ConductCognition |
| Symbol Coding | Secondary outcome | ConductCognition |
| Verbal Learning | Secondary outcome | ConductCognition |
Source 5
| Field | Value | Source |
|---|---|---|
| Release | trials-2026-11-12-0.4.0 | ClinicalTrials.gov |
| Release manifest SHA-256 | 0f4a8d8c48aee2a7573ae0fa94ecbeab70c1adbe449bbc95c424bc7d3e97b9d4 | ClinicalTrials.gov |
| Registry capture | 2026-11-12 | ClinicalTrials.gov |
| Results copy, AACT | 2026-03-23 | ClinicalTrials.gov |
| NIH clinical studies file | 2026-11-13 | ClinicalTrials.gov |
Release trials-2026-11-12-0.4.0
ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
NIH RePORTER's clinical studies and project files: Public domain (NIH RePORTER)