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Trial · NCT06168409

A Study to Investigate the Effect of Baxdrostat on Ambulatory Blood Pressure in Participants With Resistant Hypertension

NCT06168409, Phase 3, Completed, AstraZeneca

3 sourcestrials-2026-11-12-0.5.0

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ConductScience Library. A Study to Investigate the Effect of Baxdrostat on Ambulatory Blood Pressure in Participants With Resistant Hypertension. Trials, record NCT06168409. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT06168409

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Trial

As registered on ClinicalTrials.gov, in the graph's capture of the registry.

Title
A Study to Investigate the Effect of Baxdrostat on Ambulatory Blood Pressure in Participants With Resistant Hypertension
NCT number
NCT06168409
Status
Completed
Phases
Phase 3
Enrollment
218 participants, actual
Lead sponsor
AstraZeneca
Conditions
Resistant Hypertension
Interventions
Baxdrostat, Placebo
First posted
2023-12-13
Last updated
2026-08-06

Source ClinicalTrials.gov

Registered outcomes14

Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.

ListOutcomeTime frameDescription
PrimaryLeast Square Mean Difference for Change From Baseline in Ambulatory 24-hour Average SBP at Week 12: Treatment Policy StrategyBaseline to week 12
SecondaryChange From Baseline in Ambulatory Night-time Average SBP (mmHg) at Week 12 LS MeansBaseline to week 12
SecondaryChange From Baseline in Ambulatory Daytime Average SBP (mmHg) at Week 12Baseline to week 12
SecondaryChange From Baseline in Seated SBP (mmHg) at Week 12Baseline to week 12
SecondaryAchieving Ambulatory 24-hour Average SBP of < 130 mmHg at Week 12Baseline to week 12
SecondaryChange From Baseline in Ambulatory 24-hour Average DBP (mmHg) at Week 12Baseline to week 12
SecondaryChange From Baseline in Ambulatory Night-time Average DBP (mmHg) at Week 12Baseline to week 12
SecondaryChange From Baseline in Ambulatory Daytime Average DBP (mmHg) at Week 12Baseline to week 12
SecondaryChange From Baseline in Seated DBP (mmHg) at Week 12Baseline to week 12
SecondaryAchieving a Nocturnal SBP Dipping of >= 10% at Week 12Baseline to week 12

Outcomes0

Each outcome the trial posted results for, in ClinicalTrials.gov's words.

None in this release.

Results by group0

Each measurement the trial posted, group by group, in the words and numbers it posted.

None in this release.

Participant flow0

How many started, completed or left each group, period by period.

None in this release.

Adverse events0

Each adverse event the trial posted, group by group: the participants affected out of those at risk.

None in this release.

Adverse event totals0

The totals the trial posted for each group.

None in this release.

Papers3

The papers the trial lists on ClinicalTrials.gov.

PMIDListed asSource
40850955DERIVEDPubMed
40913594DERIVEDPubMed
41794437DERIVEDPubMed

Grants0

The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.

None in this release.

Trial comparisons0

Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.

None in this release.

Tests0

The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.

None in this release.

Data dates

The day each source was copied for this release.

ClinicalTrials.gov
2026-11-12
ClinicalTrials.gov
Results, from AACT
2026-03-23
AACT
NIH grant links
2026-11-13
NIH RePORTER

Sources 3

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ClinicalTrials.govNo license stated
  • NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ClinicalTrials.govnone stated
  • NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this trial from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/trials/v1/NCT06168409

GET https://conductscience.org/api/trials/v1/NCT06168409/registered