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Trial · NCT06174220

Targeted Therapy With Glycogen Synthase Kinase-3 Inhibition for Arrhythmogenic Cardiomyopathy

NCT06174220, Phase 2, Recruiting, Hamilton Health Sciences Corporation

3 sourcestrials-2026-11-12-0.5.0

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ConductScience Library. Targeted Therapy With Glycogen Synthase Kinase-3 Inhibition for Arrhythmogenic Cardiomyopathy. Trials, record NCT06174220. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT06174220

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Trial

As registered on ClinicalTrials.gov, in the graph's capture of the registry.

Title
Targeted Therapy With Glycogen Synthase Kinase-3 Inhibition for Arrhythmogenic Cardiomyopathy
NCT number
NCT06174220
Status
Recruiting
Phases
Phase 2
Enrollment
120 participants, estimated
Lead sponsor
Hamilton Health Sciences Corporation
Conditions
Arrhythmogenic Cardiomyopathy, Arrhythmogenic Right Ventricular Cardiomyopathy
Interventions
Tideglusib, Placebo
First posted
2023-12-18
Last updated
2026-03-12

Source ClinicalTrials.gov

Registered outcomes4

Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.

ListOutcomeTime frameDescription
PrimaryPVC burdenBaseline and 6 monthsChange in mean PVC count per 24 hours on 7-day Holter
SecondaryVentricular strainBaseline and 6 monthsChange in ventricular strain on echocardiography
SecondaryImplantable cardioverter-defibrillator (ICD) therapiesBaseline and 6 monthsNumber of ICD therapies (shock or anti-tachycardia pacing)
SecondarySustained ventricular tachycardia (VT) eventsBaseline and 6 monthsNumber of sustained VT events (defined as symptomatic or duration \> 30 seconds and \> 100bpm)

Outcomes0

Each outcome the trial posted results for, in ClinicalTrials.gov's words.

None in this release.

Results by group0

Each measurement the trial posted, group by group, in the words and numbers it posted.

None in this release.

Participant flow0

How many started, completed or left each group, period by period.

None in this release.

Adverse events0

Each adverse event the trial posted, group by group: the participants affected out of those at risk.

None in this release.

Adverse event totals0

The totals the trial posted for each group.

None in this release.

Papers5

The papers the trial lists on ClinicalTrials.gov.

PMIDListed asSource
24920660BACKGROUNDPubMed
27170944BACKGROUNDPubMed
31264976BACKGROUNDPubMed
31567019BACKGROUNDPubMed
35450611BACKGROUNDPubMed

Grants0

The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.

None in this release.

Trial comparisons0

Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.

None in this release.

Tests0

The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.

None in this release.

Data dates

The day each source was copied for this release.

ClinicalTrials.gov
2026-11-12
ClinicalTrials.gov
Results, from AACT
2026-03-23
AACT
NIH grant links
2026-11-13
NIH RePORTER

Sources 3

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ClinicalTrials.govNo license stated
  • NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ClinicalTrials.govnone stated
  • NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this trial from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/trials/v1/NCT06174220

GET https://conductscience.org/api/trials/v1/NCT06174220/registered