Trial · NCT06179290
Changes in Biomarker of Exposure in Adults Who Smoke Cigarettes Switching From Cigarettes to Heated Tobacco Products
NCT06179290, Not applicable, Completed, Altria Client Services LLC
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. Changes in Biomarker of Exposure in Adults Who Smoke Cigarettes Switching From Cigarettes to Heated Tobacco Products. Trials, record NCT06179290. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT06179290
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- Changes in Biomarker of Exposure in Adults Who Smoke Cigarettes Switching From Cigarettes to Heated Tobacco Products
- NCT number
- NCT06179290
- Status
- Completed
- Phases
- Not applicable
- Enrollment
- 921 participants, actual
- Lead sponsor
- Altria Client Services LLC
- Conditions
- Tobacco Use
- Interventions
- Ploom HTP Menthol HTS; MX3 (681), Ploom HTP Tobacco HTS; R8 (120), Smoking Abstinence (menthol), Smoking Abstinence (non-menthol)
- First posted
- 2023-12-21
- Last updated
- 2026-05-27
Source ClinicalTrials.gov
Registered outcomes14
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | Total 4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanol (NNAL) | Baseline through Day 5 | Total 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol (NNAL) in urine adjusted for urine creatinine (pg/mg creatinine) |
| Primary | Total N-nitrosonornicotine (NNN) | Baseline through Day 5 | Total N-nitrosonornicotine (NNN) in urine adjusted for urine creatinine (pg/mg creatinine) |
| Primary | 2-hydroxybutenylmercapturic Acid (2-MHBMA) | Baseline through Day 5 | 2-hydroxybutenylmercapturic acid (2-MHBMA) in urine adjusted for urine creatinine (ng/mg creatinine) |
| Primary | 3-hydroxypropylmercapturic Acid (3-HPMA) | Baseline through Day 5 | 3-hydroxypropylmercapturic acid (3-HPMA) in urine adjusted for urine creatinine (ng/mg creatinine) |
| Primary | S-phenyl Mercapturic Acid (SPMA) | Baseline through Day 5 | S-phenyl mercapturic acid (SPMA) in urine adjusted for urine creatinine (pg/mg creatinine) |
| Primary | 2-Hydroxyethyl Mercapturic Acid (HEMA) | Baseline through Day 5 | 2-Hydroxyethyl mercapturic acid (HEMA) in urine adjusted for urine creatinine (ng/mg creatinine) |
| Primary | 1-aminonaphthalene (1-AN) | Baseline through Day 5 | 1-aminonaphthalene (1-AN) in urine adjusted for urine creatinine (pg/mg creatinine) |
| Primary | 2-aminonaphthalene (2-AN) | Baseline through Day 5 | 2-aminonaphthalene (2-AN) in urine adjusted for urine creatinine (pg/mg creatinine) |
| Primary | 2-cyanoethyl-mercapturic Acid (CEMA) | Baseline to Day 5 | 2-cyanoethyl-mercapturic acid (CEMA) in urine adjusted for urine creatinine (ng/mg creatinine) |
| Primary | 3-hydroxybenzo[a]Pyrene (3-OH-B[a]P) | Baseline through Day 5 | 3-hydroxybenzo\[a\]pyrene (3-OH-B\[a\]P) in urine adjusted for urine creatinine (fg/mg creatinine) |
1 to 10 of 14Source ClinicalTrials.gov
See all 14 registered outcomesOutcomes0
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
None in this release.
Results by group0
Each measurement the trial posted, group by group, in the words and numbers it posted.
None in this release.
Participant flow0
How many started, completed or left each group, period by period.
None in this release.
Adverse events0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
None in this release.
Adverse event totals0
The totals the trial posted for each group.
None in this release.
Papers0
The papers the trial lists on ClinicalTrials.gov.
None in this release.
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
None in this release.
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT06179290
GET https://conductscience.org/api/trials/v1/NCT06179290/registered