Compensatory Brain Activity in Older Adults.
NCT06235840, Not applicable, Completed, Kazimierz Wielki University
Trial 10
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
| Field | Value | Source |
|---|---|---|
| Title | Compensatory Brain Activity in Older Adults. | ClinicalTrials.gov |
| NCT number | NCT06235840 | ClinicalTrials.gov |
| Status | Completed | ClinicalTrials.gov |
| Phases | Not applicable | ClinicalTrials.gov |
| Enrollment | 117 participants, actual | ClinicalTrials.gov |
| Lead sponsor | Kazimierz Wielki University | ClinicalTrials.gov |
| Conditions | Old Age; Dementia, Aging, Cognitive Decline | ClinicalTrials.gov |
| Interventions | working memory adaptive training, multi-domain non-adaptive control training | ClinicalTrials.gov |
| First posted | 2024-02-01 | ClinicalTrials.gov |
| Last updated | 2024-02-01 | ClinicalTrials.gov |
Registered outcomes 14
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description | Source |
|---|---|---|---|---|
| Primary | Change EEG power in theta, alpha and gamma bands (n-back task) | change from baseline at 4 weeks | The neural brain activity accompanying cognitive engagement during the n-back task execution. EEG data will be obtained from 32 Ag/AgCl electrodes (left: Fp1, AF3, F3, F7, FC1, FC5, C3, CP1, CP5, F7, P3, P7, PO3, O1; right: Fp2, AF4, F4, F8, FC2, FC6, C4, CP2, CP6, F8, P4, P8, PO4, O2; midline: Fz, Cz, Pz, Oz) placed in accordance with the 10-20 international system and referenced to the right and left earlobes. | ClinicalTrials.gov |
| Primary | Change n-back task | change from baseline at 4 weeks | Accuracy and reaction times in the n-back task indicated by the senstitivity index | ClinicalTrials.gov |
| Primary | Change in EEG power in theta, alpha and gamma bands (GoNoGo task) | change from baseline at 4 weeks | The neural brain activity accompanying cognitive engagement during the GoNoGo task execution. EEG data will be obtained from 32 Ag/AgCl electrodes (left: Fp1, AF3, F3, F7, FC1, FC5, C3, CP1, CP5, F7, P3, P7, PO3, O1; right: Fp2, AF4, F4, F8, FC2, FC6, C4, CP2, CP6, F8, P4, P8, PO4, O2; midline: Fz, Cz, Pz, Oz) placed in accordance with the 10-20 international system and referenced to the right and left earlobes. | ClinicalTrials.gov |
| Primary | Change in GoNoGo task | change from baseline at 4 weeks | Accuracy and reaction times in the GoNoGo task. | ClinicalTrials.gov |
| Primary | Change in EEG power in theta, alpha and gamma bands (Stroop task) | change from baseline at 4 weeks | The neural brain activity accompanying cognitive engagement during the Stroop task execution. EEG data will be obtained from 32 Ag/AgCl electrodes (left: Fp1, AF3, F3, F7, FC1, FC5, C3, CP1, CP5, F7, P3, P7, PO3, O1; right: Fp2, AF4, F4, F8, FC2, FC6, C4, CP2, CP6, F8, P4, P8, PO4, O2; midline: Fz, Cz, Pz, Oz) placed in accordance with the 10-20 international system and referenced to the right and left earlobes. | ClinicalTrials.gov |
| Primary | Change in Stroop task | change from baseline at 4 weeks | Accuracy and reaction times in the Stroop task | ClinicalTrials.gov |
| Primary | Change in OSpan task | change from baseline at 4 weeks | Accuracy in the OSpan task | ClinicalTrials.gov |
| Secondary | Change in Digit Span | change from baseline at 4 weeks | The Digit Span Subtest from the Wechsler Adult Intelligence Scale - WAIS-R (PL) | ClinicalTrials.gov |
| Secondary | Change in Digit-Symbol | change from baseline at 4 weeks | The Digit-Symbol Coding Subtest from the Wechsler Adult Intelligence Scale - WAIS-R (PL) | ClinicalTrials.gov |
| Secondary | Change in Raven's SPM | change from baseline at 4 weeks | Raven's Standard Progressive Matrices: Classic form in Polish standardisation / Parallel form n Polish standardization. minimum and maximum values (raw score): 0-60, higher scores mean a better outcome | ClinicalTrials.gov |
| Other | M.I.N.I. Screen 7.0.2 | On the first day of participation in the study, successively for the following participants over 3 years | A structured diagnostic interview - Mini International Neuropsychiatric Interview - The M.I.N.I. Screen 7.0.2. - to screen for the presence of psychiatric disorders | ClinicalTrials.gov |
| Other | Structured interview | On the first day of participation in the study, successively for the following participants over 3 years | • A structured interview, constructed for the purpose of the study: to gather information about age, neurodegenerative diseases, severe head injuries, vision defects | ClinicalTrials.gov |
| Other | MMSE | On the 1st day of participation in the study of each older adult, successively for the following participants over 3 years | Mini Mental State Examination - MMSE: to screen for dementia in older adults; the minimum and maximum values: 0-30, higher scores mean a better outcome | ClinicalTrials.gov |
| Other | ACE III | On the 1st day of participation in the study of each older adult, successively for the following participants over 3 years | • The Addenbrooke's Cognitive Examination III - ACE III: to screen for the presence of cognitive impairment in older adults; minimum and maximum values: 0-100, higher scores mean a better outcome | ClinicalTrials.gov |
Outcomes 0
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
| Type | Outcome | Time frame | Population | Units | Measured as | Source |
|---|
Results by group 0
Each measurement the trial posted, group by group, in the words and numbers it posted.
| Outcome | Group | Category | Value | Spread | Units | Source |
|---|
Participant flow 0
How many started, completed or left each group, period by period.
| Period | Milestone | Group | Participants | Units counted | Source |
|---|
Adverse events 0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
| Type | Event | Organ system | Group | Affected | At risk | Events | Source |
|---|
Adverse event totals 0
The totals the trial posted for each group.
| Total | Group | Affected | At risk | Source |
|---|
Papers 1
The papers the trial lists on ClinicalTrials.gov.
| PMID | Listed as | Source |
|---|---|---|
| 38943197 | DERIVED | PubMed |
Grants 0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
| Project | Title | Principal investigators | Organization | Funder | Fiscal years | Source |
|---|
Trial comparisons 0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
| Comparison | Source |
|---|
Tests 7
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
| Test | Named as | Source |
|---|---|---|
| 1-Back Task | Primary outcome | ConductCognition |
| 2-Back Task | Primary outcome | ConductCognition |
| Operation Span | Primary outcome | ConductCognition |
| Stroop Color-Word Test | Primary outcome | ConductCognition |
| Digit Span Test | Secondary outcome | ConductCognition |
| Matrix Reasoning | Secondary outcome | ConductCognition |
| Symbol Coding | Secondary outcome | ConductCognition |
Source 5
| Field | Value | Source |
|---|---|---|
| Release | trials-2026-11-12-0.4.0 | ClinicalTrials.gov |
| Release manifest SHA-256 | 0f4a8d8c48aee2a7573ae0fa94ecbeab70c1adbe449bbc95c424bc7d3e97b9d4 | ClinicalTrials.gov |
| Registry capture | 2026-11-12 | ClinicalTrials.gov |
| Results copy, AACT | 2026-03-23 | ClinicalTrials.gov |
| NIH clinical studies file | 2026-11-13 | ClinicalTrials.gov |
Release trials-2026-11-12-0.4.0
ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
NIH RePORTER's clinical studies and project files: Public domain (NIH RePORTER)