Trial · NCT06237491
The Safety and Dosimetry Study of 177Lu-LNC1003 Injection
NCT06237491, Phase 1, Unknown, Yantai LNC Biotechnology Singapore PTE. LTD.
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. The Safety and Dosimetry Study of 177Lu-LNC1003 Injection. Trials, record NCT06237491. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT06237491
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- The Safety and Dosimetry Study of 177Lu-LNC1003 Injection
- NCT number
- NCT06237491
- Status
- Unknown
- Phases
- Phase 1
- Enrollment
- 12 participants, estimated
- Lead sponsor
- Yantai LNC Biotechnology Singapore PTE. LTD.
- Conditions
- Metastatic Castration-resistant Prostate Cancer, mCRPC
- Interventions
- 177Lu-LNC1003 Injection group 1, 177Lu-LNC1003 Injection group 2, 177Lu-LNC1003 Injection group 3
- First posted
- 2024-02-01
- Last updated
- 2024-07-24
Source ClinicalTrials.gov
Registered outcomes3
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | the safety of 177Lu-LNC1003 Injection | through study completion, assessed up to 2 years. | To evaluate the safety of 177Lu-LNC1003 Injection assessed from the number of patients with treatment-related adverse events using CTCAE v5.0. |
| Primary | To identify the dose-limiting toxicities (DLTs) | through cycle 1, an average of 6 weeks | To identify DLTs of escalating doses of 177Lu-LNC1003 Injection up to 70 mCi (2.59 GBq) administered intravenously to patients in their first cycle of 6 weeks. |
| Primary | To determine if the MTD is among the explored dose levels and identify the expansion phase dose | Through study completion, assessed up to 2 years | To determine if the maximum tolerated dose is among the explored dose levels and identify the recommended expansion phase dose of 177Lu-LNC1003 Injection. |
Source ClinicalTrials.gov
Outcomes0
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
None in this release.
Results by group0
Each measurement the trial posted, group by group, in the words and numbers it posted.
None in this release.
Participant flow0
How many started, completed or left each group, period by period.
None in this release.
Adverse events0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
None in this release.
Adverse event totals0
The totals the trial posted for each group.
None in this release.
Papers0
The papers the trial lists on ClinicalTrials.gov.
None in this release.
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
None in this release.
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT06237491
GET https://conductscience.org/api/trials/v1/NCT06237491/registered