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Comparing Manual and Neurocognitive Skills-While Sitting, Standing, Walking on a Treadmill and Using a Stepper.

NCT06240286, Not applicable, Completed, Mayo Clinic

Trial 10

As registered on ClinicalTrials.gov, in the graph's capture of the registry.

FieldValueSource
TitleComparing Manual and Neurocognitive Skills-While Sitting, Standing, Walking on a Treadmill and Using a Stepper.ClinicalTrials.gov
NCT numberNCT06240286ClinicalTrials.gov
StatusCompletedClinicalTrials.gov
PhasesNot applicableClinicalTrials.gov
Enrollment44 participants, actualClinicalTrials.gov
Lead sponsorMayo ClinicClinicalTrials.gov
ConditionsHealthyClinicalTrials.gov
InterventionsSitting workstation, Standing workstation, Stepping workstation, Walking workstationClinicalTrials.gov
First posted2024-02-05ClinicalTrials.gov
Last updated2024-02-05ClinicalTrials.gov

Registered outcomes 12

Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.

ListOutcomeTime frameDescriptionSource
PrimaryDouble Trouble Task ScoreDay 1, Day 2, Day 3, Day 4
The Double Trouble Task is a computer based reasoning assessment that evaluates the Stroop effect which relates to the increased difficulty a person has in naming the print color of a word when the text of that word refers to an 'incongruent' color. It evaluates the capacity to inhibit automatic word recognition by selectively focusing the attention to impede the automated access of distracting word information. In the website version, three words appear on the screen, one at the top, and two at the bottom. Subjects click the word at the bottom that matches the color at the top for 90 seconds and 1 point for each correct answer. Higher scores represent better reasoning skills \& neurocognitive function.
ClinicalTrials.gov
PrimaryGrammatical Reasoning Test ScoreDay 1, Day 2, Day 3, Day 4
The Grammatical Reasoning Test is a computer based reasoning assessment that measures the capacity of a person to reason the relationships among different objects and shapes. A statement appears at the top of the screen with two shapes at the bottom. Participants clicked on 'True' or 'False' to indicate whether the sentence accurately described the relationship between the shapes in 90 seconds and participants obtained 1 point for each correct answer. Higher scores represent better reasoning skills \& neurocognitive function.
ClinicalTrials.gov
PrimaryOdd One Out Test ScoreDay 1, Day 2, Day 3, Day 4
The Odd One Out Test is a computer based reasoning assessment which evaluates the person's Intelligence Quotient. It measures fluid intelligence or the capacity to reason abstractly and solve problems. Derived from Raven's and Cattell's intelligence tests. During the test, 9 patterns (color, shape, and number) appeared on the screen; participants chose the pattern (odd one) that differed from the others for 3 minutes and got 1 point for each correct answer. Higher scores represent better reasoning skills \& neurocognitive function.
ClinicalTrials.gov
PrimaryObject Reasoning Task ScoreDay 1, Day 2, Day 3, Day 4
The Object Reasoning Task is a computer based reasoning assessment that evaluates an individual's capability to make logical deductions from a sequence of complex images. Subjects look at 4 panels, 3 at the top and 1 at the bottom. Each panel contained four separate diagrams; subjects decided whether the panel at the bottom was the next in the series or not. It takes 3 minutes and 1 point for each correct answer. Higher scores represent better reasoning skills \& neurocognitive function.
ClinicalTrials.gov
PrimarySpatial Span Task ScoreDay 1, Day 2, Day 3, Day 4
The Spatial Span Task is a computer based memory assessment that assesses the visuospatial working memory that depends on the unitary short-term memory system. Participants must remember a sequence of flashing boxes and click to the correct order; when they make a mistake the test ends and they have 3 opportunities. When they click in the right order, the following sequence increases difficulty. 4 points are the baseline; for each correct answer subjects get 1 point; if incorrect, they lose points. Higher scores represent better memory skills \& neurocognitive function.
ClinicalTrials.gov
PrimaryMonkey Ladder Task ScoreDay 1, Day 2, Day 3, Day 4
The Monkey Ladder Task is a computer based memory assessment that assesses the visual working memory better developed in chimpanzees than humans. Participants must remember which number appears in specific boxes, after a short period, the numbers disappear and they have to click on the boxes in numerical sequence, after three errors the test ends. 2 points are the baseline. Participants get 1 point for the correct answers; if incorrect, they lose the points earned. Higher scores represent better memory skills \& neurocognitive function.
ClinicalTrials.gov
PrimaryDigit Span Task ScoreDay 1, Day 2, Day 3, Day 4
The Digit Span Task is a computer based memory assessment that evaluates the verbal working memory that allows the temporary storage and manipulation of information. Participants must remember a sequence of numbers by typing them using the keyboard; after typing the correct sequence of numbers, the difficulty increases and after 3 mistakes the test ends. Participants get 1 point for a proper sequence; if incorrect, they lose points. Higher scores represent better memory skills \& neurocognitive function.
ClinicalTrials.gov
PrimaryPaired Associates Task ScoreDay 1, Day 2, Day 3, Day 4
The Paired Associates Task is a computer based memory assessment that assesses the paired-associate learning skills, a mental skill that requires learning to pair two items in memory. When the difficulty increases, several regions in the brain activate. During the task, a set of boxes appear on the screen. The boxes open, one after the other to reveal the figure inside, and subjects must remember and click which figure appears in which box. The difficulty increases in the number of figures after clicking the correct sequence and subjects will have three opportunities. Participants get 1 point for the right answers; if incorrect, they lose the points. Higher scores represent better memory skills \& neurocognitive function.
ClinicalTrials.gov
PrimaryRotations Task ScoreDay 1, Day 2, Day 3, Day 4
The Rotations Task is a computer based concentration assessment that measures the ability to rotate objects mentally. Two rotated boxes appear on the screen, each filled with red and green squares. Participants click the boxes 'Match' or 'Mismatch' in 90 seconds, if the answer is correct, they get 8 points; if not, they lose the points. Higher scores represent better concentration skills \& neurocognitive function.
ClinicalTrials.gov
PrimaryFeature Match Task ScoreDay 1, Day 2, Day 3, Day 4
The Feature Match Task is a computer based concentration assessment that measures perception, requires concentration and focuses on complex images. Two boxes appear on the screen one at the left and the other to the right, each containing a complex array of abstract shapes. Subjects will click if the figures 'Match' or 'Mismatch' for 90 seconds. If correct, the next problem will be more difficult. The points are given according to the problem's difficulty; they can vary from 1-11and above. Higher scores represent better concentration skills \& neurocognitive function.
ClinicalTrials.gov
PrimaryPolygons Task ScoreDay 1, Day 2, Day 3, Day 4
The Polygons Task Score is a computer based concentration assessment that measures the mental ability to compare complex images. Two overlapping images appear on one side of the monitor, and another figure appears on the other side and contains just one shape. Subjects click 'Match' or 'Mismatch' to indicate if the single figure is identical or different in shape from one of the overlapping figures. Each chance will increase in difficulty. Subjects in 90 seconds will try to score as many points as they can, points per correct answer can vary from 1-6 points and above. Higher scores represent better concentration skills \& neurocognitive function.
ClinicalTrials.gov
PrimaryTyping Test ScoreDay 1, Day 2, Day 3, Day 4
The Typing Test is a computer based fine motor skills assessment. It is measured using the Split Screen Typing Program (Typing Master Inc., Helsinki, Finland). Subjects completed a 3-minute test typing as fast and accurately as they could, the top of the screen showed the text that participants had to type, and the typed text was seen at the bottom of the computer monitor. Participants typed one different script for each station. Typing speed, as well as accuracy represented by number of errors, and adjusted individual typing speed at each workstation were scored. The higher typing speed \& accuracy scores (low number of errors) represent better fine motor skills.
ClinicalTrials.gov

Outcomes 0

Each outcome the trial posted results for, in ClinicalTrials.gov's words.

TypeOutcomeTime framePopulationUnitsMeasured asSource

Results by group 0

Each measurement the trial posted, group by group, in the words and numbers it posted.

OutcomeGroupCategoryValueSpreadUnitsSource

Participant flow 0

How many started, completed or left each group, period by period.

PeriodMilestoneGroupParticipantsUnits countedSource

Adverse events 0

Each adverse event the trial posted, group by group: the participants affected out of those at risk.

TypeEventOrgan systemGroupAffectedAt riskEventsSource

Adverse event totals 0

The totals the trial posted for each group.

TotalGroupAffectedAt riskSource

Papers 1

The papers the trial lists on ClinicalTrials.gov.

PMIDListed asSource
38572691DERIVEDPubMed

Grants 0

The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.

ProjectTitlePrincipal investigatorsOrganizationFunderFiscal yearsSource

Trial comparisons 0

Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.

ComparisonSource

Tests 4

The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.

TestNamed asSource
Digit Span TestPrimary outcomeConductCognition
Letter Pair Reasoning TaskPrimary outcomeConductCognition
Paired Associate LearningPrimary outcomeConductCognition
Stroop Color-Word TestPrimary outcomeConductCognition

Source 5

FieldValueSource
Releasetrials-2026-11-12-0.4.0ClinicalTrials.gov
Release manifest SHA-2560f4a8d8c48aee2a7573ae0fa94ecbeab70c1adbe449bbc95c424bc7d3e97b9d4ClinicalTrials.gov
Registry capture2026-11-12ClinicalTrials.gov
Results copy, AACT2026-03-23ClinicalTrials.gov
NIH clinical studies file2026-11-13ClinicalTrials.gov

The same record as JSON

Release trials-2026-11-12-0.4.0

ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

NIH RePORTER's clinical studies and project files: Public domain (NIH RePORTER)