Trial · NCT06274528
Registered outcomes11
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
1 to 11 of 11
Download this page as JSON| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | Changes plasma pT181/T181 ratio of lemborexant 10 and 20 mg compared to Placebo | 6 months | plasma collection |
| Secondary | Number of participants with treatment-related adverse events | 6 months | Adverse events |
| Secondary | Measure the blood concentration of lemborexant 10 mg and 20 mg and determine the dose-response relationship with CSF pT181/T181 | 6 months | Blood collection |
| Secondary | Measure changes on blood plasma amyloid-beta isoforms (Aβ38, Aβ40, Aβ42, Aβ42/Aβ40) | 6 months | Blood collection |
| Secondary | Measure changes of CSF amyloid beta isoforms (Aβ38, Aβ40, Aβ42,Aβ42/Aβ40 ) | 6 months | CSF collection |
| Secondary | Measure changes of blood plasma p-tau/tau forms (T181, pT181, pT181/T181, S202, pS202, pS202/S202, T217, pT217, pT217/T217). | 6 months | Blood collection |
| Secondary | Measure changes of cerebrospinal fluid p-tau/tau forms (T181, pT181, S202, pS202, pS202/S202, T217, pT217, pT217/T217). | 6 months | CSF collection |
| Other | Measure changes of cerebrospinal TREM2 (exploratory) | 6 months | CSF |
| Other | Measure changes of cerebrospinal NPTX2 (exploratory) | 6 months | CSF |
| Other | Measure changes of cerebrospinal NfL (exploratory) | 6 months | CSF |
| Other | Measure changes of blood plasma NfL (exploratory) | 6 months | Blood |
Source ClinicalTrials.govtrials-2026-11-12-0.5.0
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this list from software.
Twenty rows a page, as JSON. No key.
GET https://conductscience.org/api/trials/v1/NCT06274528/registered