Trial · NCT06285539
Drug Rediscovery for Rare Immune Mediated Inflammatory Diseases
NCT06285539, Phase 2, Recruiting, UMC Utrecht
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. Drug Rediscovery for Rare Immune Mediated Inflammatory Diseases. Trials, record NCT06285539. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT06285539
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- Drug Rediscovery for Rare Immune Mediated Inflammatory Diseases
- NCT number
- NCT06285539
- Status
- Recruiting
- Phases
- Phase 2
- Enrollment
- 60 participants, estimated
- Lead sponsor
- UMC Utrecht
- Conditions
- Behcet's Disease, Idiopathic Inflammatory Myopathies, IgG4-related Disease
- Interventions
- Filgotinib
- First posted
- 2024-02-29
- Last updated
- 2026-05-12
Source ClinicalTrials.gov
Registered outcomes9
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | EQ-5D-5L | 26 weeks | Change from baseline in EuroQoL-5D-5L |
| Primary | Disease activity in Behcet's patients | 26 weeks | Change from baseline in Behcet's Disease Current Activity Form (BDCAF) |
| Primary | Disease activity in myositis patients | 26 weeks | Change from baseline in Total Improvement Score (TIS) of the International Myositis Assessment Clinical Studies (IMACS) group |
| Primary | Disease activity in IgG4-RD patients | 26 weeks | Change from baseline in IgG4-RD responder index |
| Secondary | Corticosteroid toxicity | 26 weeks | Change from baseline in Glucocorticoid Toxicity Index (GTI) |
| Secondary | Corticosteroid dosage | 26 weeks | Change from baseline in glucocorticoid dose |
| Secondary | VAS score of pain | 26 weeks | Change from baseline in pain scores on the Visual Analog Scale (0-100mm). A higher score is a worse outcome |
| Secondary | Fatigue | 26 weeks | Change from baseline in fatigue scores on the Functional Assessment of Chronic Illness Therapy - Fatigue (FACIT-F). A higher score is a worse outcome |
| Secondary | Treatment-related adverse events | 26 weeks | Number of Participants With Treatment-Related Adverse Events as Assessed by CTCAE v4.0 |
Source ClinicalTrials.gov
Outcomes0
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
None in this release.
Results by group0
Each measurement the trial posted, group by group, in the words and numbers it posted.
None in this release.
Participant flow0
How many started, completed or left each group, period by period.
None in this release.
Adverse events0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
None in this release.
Adverse event totals0
The totals the trial posted for each group.
None in this release.
Papers1
The papers the trial lists on ClinicalTrials.gov.
| PMID | Listed as |
|---|---|
| 39915014 | DERIVED |
Source PubMed
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
None in this release.
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT06285539
GET https://conductscience.org/api/trials/v1/NCT06285539/registered