Trial · NCT06294990
Klinefelter Syndrome and Testosterone Treatment in Puberty
NCT06294990, Phase 4, Recruiting, Lise Aksglæde
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. Klinefelter Syndrome and Testosterone Treatment in Puberty. Trials, record NCT06294990. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT06294990
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- Klinefelter Syndrome and Testosterone Treatment in Puberty
- NCT number
- NCT06294990
- Status
- Recruiting
- Phases
- Phase 4
- Enrollment
- 32 participants, estimated
- Lead sponsor
- Lise Aksglæde
- Conditions
- Klinefelter Syndrome
- Interventions
- Testosterone gel, Placebo
- First posted
- 2024-03-06
- Last updated
- 2025-02-19
Source ClinicalTrials.gov
Registered outcomes61
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | Changes in body fat mass | Baseline and 1 and two years | Evaluation of body fat percentage by whole body dual energy x-ray absorptiometry (DEXA) scan |
| Secondary | Pubertal development and virilization | Every three months for two years | Tanner genital (G) staging from G1 to G5. G1 is the prepubertal stage and G5 is the fully develloped stage. |
| Secondary | Pubertal development and virilization | Every three months for two years | Tanner pubic hair (PH) staging from PH1 to PH6. PH1 is the prepubertal stage and PH6 is the fully develloped stage. |
| Secondary | Pubertal development and virilization | Every three months for two years | Measurement of voice frequency using the app "Voice Analyst" (Speechtools Ltd.). |
| Secondary | Pubertal development and virilization | Every three months for two years | Evaluation of testicular volume by palpation with orchidometer |
| Secondary | Pubertal development and virilization | Every three months for two years | Presence of gynecomastia (yes/no) |
| Secondary | Pubertal development and viriliztion | Every three months for two years | Measurement of luteinizing hormone (LH) (IU/L) in serum |
| Secondary | Pubertal development and viriliztion | Every three months for two years | Measurement of serum concentration of testosterone (nmol/L) |
| Secondary | Pubertal development and viriliztion | Every three months for two years | Measurement of folliclestimulating hormone (FSH) (IU/L) in serum |
| Secondary | Pubertal development and viriliztion | Every three months for two years | Measurement of serum concentration of estradiol (pmol/L) |
1 to 10 of 61Source ClinicalTrials.gov
See all 61 registered outcomesOutcomes0
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
None in this release.
Results by group0
Each measurement the trial posted, group by group, in the words and numbers it posted.
None in this release.
Participant flow0
How many started, completed or left each group, period by period.
None in this release.
Adverse events0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
None in this release.
Adverse event totals0
The totals the trial posted for each group.
None in this release.
Papers1
The papers the trial lists on ClinicalTrials.gov.
| PMID | Listed as |
|---|---|
| 40090688 | DERIVED |
Source PubMed
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
None in this release.
Tests2
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
| Test | Named as | Source |
|---|---|---|
| Line Angle Matching | Secondary outcome | ConductCognition |
| Mental Rotation | Secondary outcome | ConductCognition |
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT06294990
GET https://conductscience.org/api/trials/v1/NCT06294990/registered?page=2