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Trial · NCT06302998

Dexmedetomidine and Vasopressin in Septic Shock

NCT06302998, Phase 2, Unknown, Mansoura University

3 sourcestrials-2026-11-12-0.5.0

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ConductScience Library. Dexmedetomidine and Vasopressin in Septic Shock. Trials, record NCT06302998. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT06302998

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Trial

As registered on ClinicalTrials.gov, in the graph's capture of the registry.

Title
Dexmedetomidine and Vasopressin in Septic Shock
NCT number
NCT06302998
Status
Unknown
Phases
Phase 2
Enrollment
260 participants, estimated
Lead sponsor
Mansoura University
Conditions
Sepsis, Septic Shock
Interventions
DEX-PRESSIN, Standard of Care
First posted
2024-03-12
Last updated
2024-03-12

Source ClinicalTrials.gov

Registered outcomes12

Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.

ListOutcomeTime frameDescription
Primaryin-hospital mortalitythroughout the hospitalization period on average 90 days.All-cause inhospital mortality as a binary outcome
Secondarysurvival analysisthrough out the hospitalization period or 28 days after inclusion if discharged from hosptia; before 28 daystime to die using Kaplan Mier Curve
SecondaryNorepinephrine Equivalent Dose (NED)over the first three days after enrolment or deathmean NED over the first three days after enrolment or death, whichever comes first; the NED of epinephrine will be estimated as a 1:1 ratio
SecondaryDuration of vasopressor infusion in survivorsthrough out the hospitalization period or 28 days after inclusion if discharged from hosptial before 28 daysDuration in hours from the start of the vasopressor (NE or vasopressin) infusion till the time of discontinuation.
SecondaryInitiation of invasive mechanical ventilation (IMV)through out the hospitalization period or 28 days after inclusion if discharged from hosptial before 28 daysincidence of IMV
SecondaryDuration of IMVthrough out the hospitalization period or 28 days after inclusion if discharged from hosptial before 28 daysduratioin in hours
SecondaryEarly acute kidney injury (AKI)within 48 hoursAKI according to the KDIGO guidelines 2012
SecondaryLate acute kidney injury (AKI)between 48 hours and 7 daysAKI according to the KDIGO guidelines 2012
SecondaryAcute Physiology and Chronic Health Evaluation (APACHE-II)on the 3rd day after enrollmentAs a score on MedCalc
SecondarySimplified Acute Physiology Score (SAPS) II scoreon the 3rd day after enrollmentAs a score on MedCalc

Outcomes0

Each outcome the trial posted results for, in ClinicalTrials.gov's words.

None in this release.

Results by group0

Each measurement the trial posted, group by group, in the words and numbers it posted.

None in this release.

Participant flow0

How many started, completed or left each group, period by period.

None in this release.

Adverse events0

Each adverse event the trial posted, group by group: the participants affected out of those at risk.

None in this release.

Adverse event totals0

The totals the trial posted for each group.

None in this release.

Papers0

The papers the trial lists on ClinicalTrials.gov.

None in this release.

Grants0

The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.

None in this release.

Trial comparisons0

Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.

None in this release.

Tests0

The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.

None in this release.

Data dates

The day each source was copied for this release.

ClinicalTrials.gov
2026-11-12
ClinicalTrials.gov
Results, from AACT
2026-03-23
AACT
NIH grant links
2026-11-13
NIH RePORTER

Sources 3

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ClinicalTrials.govNo license stated
  • NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ClinicalTrials.govnone stated
  • NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this trial from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/trials/v1/NCT06302998

GET https://conductscience.org/api/trials/v1/NCT06302998/registered