Trial · NCT06319274
Infusion of Prostacyclin vs Placebo for 72-hours in Mechanically Ventilated Patients With Acute Respiratory Failure
NCT06319274, Phase 2, Recruiting, Pär Johansson
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. Infusion of Prostacyclin vs Placebo for 72-hours in Mechanically Ventilated Patients With Acute Respiratory Failure. Trials, record NCT06319274. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT06319274
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- Infusion of Prostacyclin vs Placebo for 72-hours in Mechanically Ventilated Patients With Acute Respiratory Failure
- NCT number
- NCT06319274
- Status
- Recruiting
- Phases
- Phase 2
- Enrollment
- 450 participants, estimated
- Lead sponsor
- Pär Johansson
- Conditions
- Acute Respiratory Failure, Endothelial Dysfunction, Pulmonary Infection
- Interventions
- Iloprost, Isotonic saline
- First posted
- 2024-03-20
- Last updated
- 2025-08-22
Source ClinicalTrials.gov
Registered outcomes7
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | 28-day mortality | Day 28 | All-cause mortality at day 28 |
| Secondary | 90-day mortality | Day 90 | All-cause mortality at day 90 |
| Secondary | Vasopressor-free days | Until ICU discharge, maximun 90 days after randomization] | Days alive without vasopressor in the ICU within 28- and 90 days |
| Secondary | Renal replacement-free days | Until ICU discharge, maximun 90 days after randomization] | Days alive without renal replacement in the ICU within 28- and 90 days |
| Secondary | Mechanical ventilation free days | Until ICU discharge, maximun 90 days after randomization] | Days alive without mechanical ventilation in the ICU within 28- and 90 days |
| Secondary | Serious adverse reactions (SARs) | Until day 7 after randomization | Total number and numbers of patient with one or more serious adverse reactions within the first 7 days |
| Secondary | Serious adverse events (SAEs) | Until day 7 after randomization | Total numbers and numbers of patients with one or more serious adverse events within the first 7 days |
Source ClinicalTrials.gov
Outcomes0
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
None in this release.
Results by group0
Each measurement the trial posted, group by group, in the words and numbers it posted.
None in this release.
Participant flow0
How many started, completed or left each group, period by period.
None in this release.
Adverse events0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
None in this release.
Adverse event totals0
The totals the trial posted for each group.
None in this release.
Papers0
The papers the trial lists on ClinicalTrials.gov.
None in this release.
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
None in this release.
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT06319274
GET https://conductscience.org/api/trials/v1/NCT06319274/registered