Trial · NCT06327152
Caffeine Use in the Management of Preterm Infants
NCT06327152, Phase 2, Active not recruiting, University of California, Irvine
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. Caffeine Use in the Management of Preterm Infants. Trials, record NCT06327152. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT06327152
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- Caffeine Use in the Management of Preterm Infants
- NCT number
- NCT06327152
- Status
- Active not recruiting
- Phases
- Phase 2
- Enrollment
- 80 participants, estimated
- Lead sponsor
- University of California, Irvine
- Conditions
- Apnea of Prematurity
- Interventions
- Caffeine, Sterile Water Placebo
- First posted
- 2024-03-25
- Last updated
- 2025-11-10
Source ClinicalTrials.gov
Registered outcomes5
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | Time to full feeds | From first nutritive oral feed until full oral feeds achieved, up to 6 weeks | The primary outcome is time (in days) to full oral bottle feeding or breastfeeding or a combination of both. Full oral bottle feeding is defined as 48 hours of consistent intake of at least 150ml/kg/day of formula or breastmilk. If the subject is on combination of bottle and breastfeeding, two consecutive days of positive weight gain will be used in place of 150ml/kg/day as primary outcome measure. |
| Secondary | Time to discharge | Randomization until discharge, up to 6 weeks | Time to discharge measured in days of hospitalization after randomization |
| Secondary | Post menstrual age (PMA) at time of discharge | Randomization until discharge, up to 6 weeks | Post menstrual age at discharge |
| Secondary | Number of significant cardiopulmonary events | Randomization until discharge, up to 6 weeks | Number of significant cardiopulmonary events defined as apnea \> 20 seconds, apnea with heart rate (HR) \< 80 beats per minute (bpm), HR \< 80 bpm with desaturation \< 85% or color change. Significant events are ones that occur while infant is asleep or lying down. |
| Secondary | Weight change | Randomization until discharge, up to 6 weeks | Weight change measured by change in grams |
Source ClinicalTrials.gov
Outcomes0
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
None in this release.
Results by group0
Each measurement the trial posted, group by group, in the words and numbers it posted.
None in this release.
Participant flow0
How many started, completed or left each group, period by period.
None in this release.
Adverse events0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
None in this release.
Adverse event totals0
The totals the trial posted for each group.
None in this release.
Papers0
The papers the trial lists on ClinicalTrials.gov.
None in this release.
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
None in this release.
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT06327152
GET https://conductscience.org/api/trials/v1/NCT06327152/registered