Trial · NCT06344442
Registered outcomes14
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
1 to 14 of 14
Download this page as JSON| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | The primary objective is to compare the effect of intraoperative low-dose supplementation of AVP vs norepinephrine infusions on post-transplant Acute Kidney Injury after liver transplantation. | during the first 7 postoperative days | The stages of AKI according to AKI Network criteria (KDIGO score) determined by changes in serum creatinine and changes in urine output. |
| Secondary | To compare into the two arms the number of packed red blood cellsand fresh frozen plasma transfused | during the first 12 hours postoperatively | |
| Secondary | To compare into the two arms the number of the Number of AKI KDIGO 1 | 1 during the first 7days | defined as increase in serum creatinine concentration by 1.5 to 1.9 fold or ≥0.3mg/dl (or 27 micromol/L) within 48h or urine output \<0.5 ml/Kg/h over a period 6-12 h) |
| Secondary | To compare into the two arms the Number of AKI KDIGO 2 | during the first 7 postoperative | defined as increase in serum creatinine concentration by 2.0 to 2.9 fold or urine output \<0.5 ml/Kg/h over a period ≥12 h) |
| Secondary | To compare into the Number of AKI KDIGO 3 | during the first 7 postoperative | defined as increase in serum creatinine concentration ≥ 3 fold or ≥ 4mg/dl (or 354 micromol/L) or urine output \<0.3 ml/Kg/h for ≥24h or anuria\>12h) |
| Secondary | The need for renal replacement for replacement therapy (RRT) in ICU | during the first 7 days postoperatively and on postoperative day 30 | |
| Secondary | The number of patients remaining on dialysis at the end of the study | on the 30th Day | |
| Secondary | Average intraoperative norepinephrine concentrations | intraoperative | |
| Secondary | Average intraoperative concentrations of other vasopressors and inotropes (Adrenalin, Dobutamine) | intraoperative | |
| Secondary | Number of platelets transfused intraoperatively | during the first 12 hours postoperatively. | |
| Secondary | Amount of vascular filling solutions intraoperatively | During the first 12 hours postoperatively. | |
| Secondary | Sequential Organ Failure Assessment (SOFA score) | On the third and seventh postoperative day | Sequential Organ Failure Assessment (SOFA score between 0 and 24). Zero indicates that the patient has no organ dysfunction, twenty-four is the maximum score and indicates that the patient has vinght four is the maximum score and indicates that the patient has all 6 of the organ dysfunctions explored. (respiratory, coagulatory, liver, cardiovascular, renal, and neurologic) |
| Secondary | Number of days alive outside intensive care unit | during the 30 day post-operation | |
| Secondary | Mortality | at 30 days |
Source ClinicalTrials.govtrials-2026-11-12-0.5.0
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this list from software.
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GET https://conductscience.org/api/trials/v1/NCT06344442/registered