Trial · NCT06353061
Chemoradiotherapy With or Without Metformin in Locally Advanced Cervical Cancer
NCT06353061, Phase 2, Unknown, Peking Union Medical College Hospital
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. Chemoradiotherapy With or Without Metformin in Locally Advanced Cervical Cancer. Trials, record NCT06353061. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT06353061
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- Chemoradiotherapy With or Without Metformin in Locally Advanced Cervical Cancer
- NCT number
- NCT06353061
- Status
- Unknown
- Phases
- Phase 2
- Enrollment
- 51 participants, estimated
- Lead sponsor
- Peking Union Medical College Hospital
- Conditions
- Cervical Cancer, Radiotherapy, Metformin, Hypoxia, PET/CT
- Interventions
- Metformin, Radiotherapy, Chemotherapy, PET/CT
- First posted
- 2024-04-08
- Last updated
- 2025-01-14
Source ClinicalTrials.gov
Registered outcomes5
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | The degree to which metformin improves the hypoxic index measured by CAIX PET | 1week after randomization | Using the uptake value parameter of CA-IX in PET/CT, comparing the changes in uptake values between the two scans as an indicator of improvement in hypoxia level |
| Secondary | Progression-free survival（PFS） | 2-year | Progression-free survival is defined as the time from randomization to disease progression or death from any cause,whichever is first. |
| Secondary | Changes in tumor volume during treatment | Baseline，1month and 2 months. | Tumor volume will be measured via pelvic MRI. |
| Secondary | Hematologic and gastrointestinal toxicities assessed by CTCAE v5.0 | Up to 3 months after treatment. | Treatment-related toxicity reactions in both groups of patients will be evaluated during the treatment period, at the end of treatment, and three months after treatment completion |
| Secondary | Quality of life assessed by QLQ-C30 | Up to 3 months after treatment | Assessment of quality of life in both groups of patients |
Source ClinicalTrials.gov
Outcomes0
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
None in this release.
Results by group0
Each measurement the trial posted, group by group, in the words and numbers it posted.
None in this release.
Participant flow0
How many started, completed or left each group, period by period.
None in this release.
Adverse events0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
None in this release.
Adverse event totals0
The totals the trial posted for each group.
None in this release.
Papers0
The papers the trial lists on ClinicalTrials.gov.
None in this release.
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
None in this release.
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT06353061
GET https://conductscience.org/api/trials/v1/NCT06353061/registered