Trial · NCT06367283
Registered outcomes23
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
1 to 20 of 23
Download this page as JSON| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | Finger pain | Week 16 | Change from baseline in Visual Analogue Scale (VAS) finger joint pain of the target hand after 16 weeks of treatment |
| Secondary | Function | Week 16 | Change from baseline after 16 weeks of treatment in physical function assessed by Australian/Canadian Osteoarthritis Hand Index (AUSCAN) physical function subscale |
| Secondary | Thumb base pain | Week 16 | Change from baseline after 16 weeks of treatment in Visual Analogue Scale thumb base pain of the target hand |
| Secondary | Hand pain | Week 16 | Change from baseline after 16 weeks of treatment in pain of both hands assessed by Australian/Canadian Osteoarthritis Hand Index hand pain subscale |
| Secondary | Physician tender joint count | Week 16 | Change from baseline after 16 weeks of treatment in joint activity of the target hand assessed by physician tender joint count |
| Secondary | Patient global assessment | Week 16 | Change from baseline after 16 weeks of treatment in Visual Analogue Scale patient global assessment |
| Secondary | Quality of life assessed by the European Quality of life - 5 dimensions (EQ-5D) scale | Week 16 | Change from baseline after 16 weeks of treatment in quality of life assessed by the European Quality of life - 5 dimensions scale |
| Secondary | Hand strength | Week 16 | Change from baseline after 16 weeks of treatment in hand strength of the target hand assessed by a grip dynamometer |
| Secondary | Number of treatment responders | Week 16 | Responders will be identified according to OMERACT-OARSI criteria, defined as (1) improvement in finger pain (primary outcome) or function (secondary outcome) ≥50% and an absolute change ≥20 mm; or (2) improvement of ≥20% with an absolute change ≥10 mm in at least two of the following three: finger pain (primary outcome), function (secondary outcome), and patient global assessment (secondary outcome). |
| Other | Stiffness of both hands | Week 16 | Change in stiffness of both hands measured on the Australian/Canadian Osteoarthritis Hand Index (AUSCAN) stiffness subscale |
| Other | Composite of pain, function and stiffness | Week 16 | Change in pain, function and stiffness of both hands measured composite on the Australian/Canadian Osteoarthritis Hand Index (AUSCAN) Hand Index Score |
| Other | Physical function | Week 16 | Change in physical function of both hands assessed by the Health Assessment Questionnaire Disability Index (HAQ-DI) |
| Other | Physician global assessment | Week 16 | Change in physician global assessment of disease activity of hand OA in the target hand measured on a Visual Analogue Scale (VAS) scale |
| Other | Swollen joint count | Week 16 | Change in physician swollen joint count of the target hand |
| Other | Fatigue | Week 16 | Change in fatigue measured on a Visual Analogue Scale (VAS) scale |
| Other | Sleep quality | Week 16 | Change in sleep quality measured on the Pittsburgh Sleep Quality Index (PSQI) |
| Other | Absence or presence of inflammation of target hand | Week 16 | Change in absence or presence of inflammation of the target hand as measured by ultrasound (US) |
| Other | Change in use of analgesics | Week 16 | Change in use of analgesics measured as the use of paracetamol and NSAIDS |
| Other | Inflammatory biomarker | Week 16 | Change in hsCRP mg/L |
| Other | Metabolic outcomes | Week 16 | Change in HbA1c mmol/mol |
Source ClinicalTrials.govtrials-2026-11-12-0.5.0
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
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GET https://conductscience.org/api/trials/v1/NCT06367283/registered