Trial · NCT06372561
Comparative Evaluation of Melatonin Versus MTA on Vital Pulp Therapy in Young Permanent First Molars: An in Vivo Study
NCT06372561, Not applicable, Unknown, Suez Canal University
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. Comparative Evaluation of Melatonin Versus MTA on Vital Pulp Therapy in Young Permanent First Molars: An in Vivo Study. Trials, record NCT06372561. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT06372561
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- Comparative Evaluation of Melatonin Versus MTA on Vital Pulp Therapy in Young Permanent First Molars: An in Vivo Study
- NCT number
- NCT06372561
- Status
- Unknown
- Phases
- Not applicable
- Enrollment
- 45 participants, estimated
- Lead sponsor
- Suez Canal University
- Conditions
- Dental Caries in Children, Vital Pulp Therapy
- Interventions
- Mineral trioxide aggregate (dressing material), Melatonin (dressing material)
- First posted
- 2024-04-18
- Last updated
- 2024-08-02
Source ClinicalTrials.gov
Registered outcomes8
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | Clinically assessment (Modified visual analogue scale) | Immediately after apexogenesis procedure, after 1 month, 3 months, 6 months, 9 months and 12 months | Pain, sensitivity to percussion (scale values from 0 to 10) 0 means no pain and 10 means the worst pain with failure of the treatment. |
| Primary | Clinically assessment (Millar's index) | Immediately after apexogenesis procedure, after 1 month, 3 months, 6 months, 9 months and 12 months | tooth mobility (classes I,II,III) from less mobility to higher mobility. |
| Primary | Clinically assessment (presence or abscence) | Immediately after apexogenesis procedure, after 1 month, 3 months, 6 months, 9 months and 12 months | changes in mucobuccal folds (swelling, redness, abscess,fistula) |
| Primary | Radiographic assessment (using Image J software program) | Immediately after apexogenesis procedure, after 1 month, 3 months, 6 months, 9 months and 12 months | Density of calcific tissue (dentinal bridge) underneath MTA, Melatonin and their mixture (the 3 groups) (Densitometric analysis) |
| Primary | Radiographic assessment (using Image J software program) | Immediately after apexogenesis procedure, after 1 month, 3 months, 6 months, 9 months and 12 months | Thickness of calcific tissue (dentinal bridge) underneath MTA, Melatonin and their mixture (the 3 groups) |
| Primary | Radiographic assessment (using Image J software program) | Immediately after apexogenesis procedure, after 1 month, 3 months, 6 months, 9 months and 12 months | Width of apical foramina for the 3 groups. |
| Primary | Radiographic assessment (using Image J software program) | Immediately after apexogenesis procedure, after 1 month, 3 months, 6 months, 9 months and 12 months | Linear radiographic measurement of root development. |
| Primary | Radiographic assessment (using Image J software program) | Immediately after apexogenesis procedure, after 1 month, 3 months, 6 months, 9 months and 12 months | Assessment of changes in bone density surrounding the treated teeth (Densiometric analysis) |
Source ClinicalTrials.gov
Outcomes0
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
None in this release.
Results by group0
Each measurement the trial posted, group by group, in the words and numbers it posted.
None in this release.
Participant flow0
How many started, completed or left each group, period by period.
None in this release.
Adverse events0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
None in this release.
Adverse event totals0
The totals the trial posted for each group.
None in this release.
Papers3
The papers the trial lists on ClinicalTrials.gov.
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
None in this release.
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT06372561
GET https://conductscience.org/api/trials/v1/NCT06372561/registered