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Trial · NCT06422975

Registered outcomes13

Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.

ListOutcomeTime frameDescription
PrimaryCharacterise the clinical practice of vasopressin use in the context of shock in a multicentre observational study.90 daysDescribing the time sequence of vasopressin and/or noradrenaline use (what is initiated first) during shock
SecondaryAssess what prompted the decision to initiate AVPUp to 7 daysAssess what prompted the decision to initiate AVP: type of shock (vasoplegic, hypovolemic,...), perfusion parameters (as lactate) or noradrenaline dose (microgram/kg/minute)
SecondaryDefine the impact of starting AVP on noradrenaline doseUp to 7 daysDefine the impact of starting AVP on noradrenaline dose (microgram/kg/minute)
SecondaryDefine the impact of starting AVP on lactate levelUp to 7 daysDefine the impact of starting AVP on lactate level (mmol/L)
SecondaryObserve when AVP is discontinued and howUp to 7 daysDescribe number of participants what AVP is discontinued first and how (abruptly or progressively)
SecondaryEstimate the range of doses of AVP usedUp to 7 daysEstimate the range of doses of AVP used and the maximum dose used in routine clinical practice.
SecondaryIncidence of side effectsUp to 7 daysDescribe the incidence of side effects, whether it is related to AVP dose and patients' comorbidities.
Secondary28-day all-cause mortality28 daysDeath on or before study day 28
Secondary90-day all-cause mortality90 daysDeath on or before study day 90
SecondaryIncidence of new renal replacement therapyFrom onset of shock until hospital discharge, an average of 2 weeksNew receipt of renal replacement therapy after onset of shock
SecondaryVasopressor-free days to day 2828 daysNumber of days between day 28 and the end of the last period of vasopressor therapy prior to day 28
SecondaryIntensive care unit-free days to day 2828 daysNumber of days between day 28 and the end of the last period of intensive care unit admission prior to day 28.
SecondaryHospital-free days to day 2828 daysNumber of days between day 28 and the end of the last period of hospital admission prior to day 28

Source ClinicalTrials.govtrials-2026-11-12-0.5.0

Sources 3

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ClinicalTrials.govNo license stated
  • NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ClinicalTrials.govnone stated
  • NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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