Trial · NCT06431776
Inhaled Molgramostim in Pediatric Participants With Autoimmune Pulmonary Alveolar Proteinosis (aPAP).
NCT06431776, Phase 3, Recruiting, Savara Inc.
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. Inhaled Molgramostim in Pediatric Participants With Autoimmune Pulmonary Alveolar Proteinosis (aPAP). Trials, record NCT06431776. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT06431776
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- Inhaled Molgramostim in Pediatric Participants With Autoimmune Pulmonary Alveolar Proteinosis (aPAP).
- NCT number
- NCT06431776
- Status
- Recruiting
- Phases
- Phase 3
- Enrollment
- 5 participants, estimated
- Lead sponsor
- Savara Inc.
- Conditions
- Autoimmune Pulmonary Alveolar Proteinosis
- Interventions
- Molgramostim
- First posted
- 2024-05-29
- Last updated
- 2026-02-19
Source ClinicalTrials.gov
Registered outcomes12
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | DLCO | 24 weeks | Change in Hb-adjusted % predicted DLCO from Baseline. |
| Secondary | DLCO | 48-weeks | Change in Hb-adjusted % predicted DLCO from Baseline . |
| Secondary | 6-minute walk distance | 24-weeks | Absolute change from Baseline in 6-minute walk distance (6MWD) |
| Secondary | 6-minute walk distance | 48-weeks | Absolute change from Baseline in 6-minute walk distance (6MWD). |
| Secondary | PedsQL | 24-weeks | Change from Baseline in Pediatric Quality of Life (PedsQLTM) Generic Core Scale score. |
| Secondary | PedsQL | 48-weeks | Change from Baseline in Pediatric Quality of Life (PedsQLTM) Generic Core Scale score. |
| Secondary | Oxygen Saturation (SpO2) | 24 weeks | Absolute change from Baseline in oxygen saturation (SpO2) |
| Secondary | Oxygen Saturation (SpO2) | 48 weeks | Absolute change from Baseline in oxygen saturation (SpO2) |
| Other | Adverse Events | 48 weeks | Adverse events (AEs), including clinically significant findings on pulmonary function tests and safety laboratory assessments and adverse events of special interest (AESIs; hypersensitivity and chest pain). |
| Other | Anti-GM-CSF Ab titer | 0, 4, 12,24,48 and 52 weeks | Titers of anti-GM-CSF antibodies |
1 to 10 of 12Source ClinicalTrials.gov
See all 12 registered outcomesOutcomes0
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
None in this release.
Results by group0
Each measurement the trial posted, group by group, in the words and numbers it posted.
None in this release.
Participant flow0
How many started, completed or left each group, period by period.
None in this release.
Adverse events0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
None in this release.
Adverse event totals0
The totals the trial posted for each group.
None in this release.
Papers0
The papers the trial lists on ClinicalTrials.gov.
None in this release.
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
None in this release.
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT06431776
GET https://conductscience.org/api/trials/v1/NCT06431776/registered