Trial · NCT06439524
The Effect of Medical Management Following Excisional Surgery for Endometriosis: A Randomized Controlled Trial
NCT06439524, Phase 3, Recruiting, Main Line Health
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. The Effect of Medical Management Following Excisional Surgery for Endometriosis: A Randomized Controlled Trial. Trials, record NCT06439524. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT06439524
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- The Effect of Medical Management Following Excisional Surgery for Endometriosis: A Randomized Controlled Trial
- NCT number
- NCT06439524
- Status
- Recruiting
- Phases
- Phase 3
- Enrollment
- 110 participants, estimated
- Lead sponsor
- Main Line Health
- Conditions
- Endometriosis
- Interventions
- 40 mg relugolix, 1 mg estradiol, 0.5 mg norethindrone acetate
- First posted
- 2024-06-03
- Last updated
- 2026-06-12
Source ClinicalTrials.gov
Registered outcomes7
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | This study aims to determine if immediate postoperative medical suppression with Regugolix combination therapy (Rel-CT) following excisional surgery for endometriosis is superior to surgery alone. | 6 months | The study will assess quality of life via change in total Endometriosis Health Profile 30 (EHP-30) scores following excisional surgery for endometriosis from baseline to 6 months postoperatively. |
| Secondary | Change in EHP-30 scores between groups stratified by endometriosis stage | 6 months | Comparison of EHP-30 scores according to endometriosis stage of the participant of Rel-CT group to non Rel-Ct treatment group |
| Secondary | Comparison of EHP-30 subscales | 6 months | Comparison of EHP-30 survey subscales in treatment groups. |
| Secondary | Comparison of EHP-30 by superficial vs deep infiltrating types | 6 months | Comparison of EHP-30 scores according to the participant having superficial or deep infiltrating endometriosis post-surgery. |
| Secondary | Reintervention rates between groups | 6 months | Need for surgical reintervention will be assessed between treatment groups. |
| Secondary | Compliance rates for the study drug and office visits following surgery | 6 months | Study drug adherence will be monitored and reported. |
| Secondary | Rates of concomitant adenomyosis | 6 months | Rate of concomitant adenomyosis will be collected and compared between two treatment groups. |
Source ClinicalTrials.gov
Outcomes0
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
None in this release.
Results by group0
Each measurement the trial posted, group by group, in the words and numbers it posted.
None in this release.
Participant flow0
How many started, completed or left each group, period by period.
None in this release.
Adverse events0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
None in this release.
Adverse event totals0
The totals the trial posted for each group.
None in this release.
Papers0
The papers the trial lists on ClinicalTrials.gov.
None in this release.
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
None in this release.
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT06439524
GET https://conductscience.org/api/trials/v1/NCT06439524/registered