Trial · NCT06451666
Safety and Efficacy Study of Pilocarpine HCl Ophthalmic Solution in Participants With Presbyopia
NCT06451666, Phase 3, Unknown, CSPC Ouyi Pharmaceutical Co., Ltd.
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. Safety and Efficacy Study of Pilocarpine HCl Ophthalmic Solution in Participants With Presbyopia. Trials, record NCT06451666. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT06451666
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- Safety and Efficacy Study of Pilocarpine HCl Ophthalmic Solution in Participants With Presbyopia
- NCT number
- NCT06451666
- Status
- Unknown
- Phases
- Phase 3
- Enrollment
- 330 participants, estimated
- Lead sponsor
- CSPC Ouyi Pharmaceutical Co., Ltd.
- Conditions
- Presbyopia
- Interventions
- Pilocarpine HCl Ophthalmic Solution, Vehicle
- First posted
- 2024-06-11
- Last updated
- 2024-07-03
Source ClinicalTrials.gov
Registered outcomes9
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | Title: Percentage of Participants Gaining 3 Lines or More in Mesopic, High-contrast, Binocular Distance-Corrected Near Visual Acuity (DCNVA) at Day 30, Hour 3 | Baseline (Day 1) to Day 30 (Hour 3) | |
| Secondary | Incidence and frequency of adverse events (AE) and serious adverse events (SAE) etc. | Through study completion, an average of 60 days | |
| Secondary | Area under the plasma concentration time curve from time zero to the last measurable concentration(AUC0-t) | Day 1 and Day 30 | |
| Secondary | Area under the plasma concentration-time curve from time zero to infinity(AUC0-inf) | Day 1 and Day 30 | |
| Secondary | Maximum plasma concentration(Cmax) | Day 1 and Day 30 | |
| Secondary | Time to maximum plasma concentration (Tmax) | Day 1 and Day 30 | |
| Secondary | Apparent Volume of Distribution During Terminal Phase (Vz/F) | Day 1 and Day 30 | |
| Secondary | Apparent Terminal Elimination Half-Life (T1/2) | Day 1 and Day 30 | |
| Secondary | Apparent total body clearance (CL/F) | Day 1 and Day 30 |
Source ClinicalTrials.gov
Outcomes0
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
None in this release.
Results by group0
Each measurement the trial posted, group by group, in the words and numbers it posted.
None in this release.
Participant flow0
How many started, completed or left each group, period by period.
None in this release.
Adverse events0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
None in this release.
Adverse event totals0
The totals the trial posted for each group.
None in this release.
Papers0
The papers the trial lists on ClinicalTrials.gov.
None in this release.
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
None in this release.
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT06451666
GET https://conductscience.org/api/trials/v1/NCT06451666/registered