Trial · NCT06453694
Registered outcomes35
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
21 to 35 of 35
Download this page as JSON| List | Outcome | Time frame | Description |
|---|---|---|---|
| Secondary | Visual fields | 6 months | Difference in change in Humphrey Visual fields score from baseline to each assessment time point between groups. Data derived from automated perimetry are continuous and expressed in decibels. The mean deviation calculated from a Humphrey Visual Field analyzer (24-2 fast paradigm) represents the difference between an individual's test performance and the performance of a normally-sighted control of the same age. |
| Secondary | Vision Related Quality of Life | 6 months | National Eye Institute Visual Functioning Questionnaire (VFQ-25) scores at baseline, 1 month, 3 months, and 6 months in each arm. Scores range from 0 = worst to 100 = best |
| Secondary | Efgartigimod safety measures | 6 months | Frequency and type of overall adverse events, treatment-related adverse events, and serious adverse events |
| Other | Number and proportion of patients enrolled within 3, 5, 7, and 10 days of visual symptom onset | Day 0 | Number and proportion of patients enrolled within 3, 5, 7, and 10 days of visual symptom onset |
| Other | Contrast enhancement | Day 0 | Number and proportion of patients enrolled with contrast enhancement of the optic nerves on MRI |
| Other | Median duration (in days) from onset of blurry vision or visual acuity change to randomization | Day 0 | Median duration (in days) from onset of blurry vision or visual acuity change to randomization |
| Other | Median duration (in days) from onset of eye pain or headache to randomization | Day 0 | Median duration (in days) from onset of eye pain or headache to randomization |
| Other | Number and proportion of overall participants with each diagnosis | Day 30 | Number and proportion of overall participants with a final diagnosis of AQP4+ NMOSD, seronegative NMOSD, MOGAD, MS-related optic neuritis, idiopathic acute optic neuritis, or other diagnosis |
| Other | Proportion amongst screened and recruited participants with HCVA of each visual acuity severity | Day 0 | Proportion amongst screened and recruited participants with HCVA worse than logMAR 0.48 (20/60), logMAR 0.7 (20/100), and logMAR 1 (20/200) |
| Other | Retinal nerve fiber layer (RNFL) thickness at 1 month between groups | 1 month | Retinal nerve fiber layer (RNFL) thickness at 1 month between groups |
| Other | Retinal nerve fiber layer (RNFL) thickness at 3 months between groups | 3 months | Retinal nerve fiber layer (RNFL) thickness at 3 months between groups |
| Other | Retinal nerve fiber layer (RNFL) thickness at 6 months between groups | 6 months | Retinal nerve fiber layer (RNFL) thickness at 6 months between groups |
| Other | Ganglion cell layer (GCL) thickness at 1 month between groups | 1 month | Ganglion cell layer (GCL) thickness at 1 month between groups |
| Other | Ganglion cell layer (GCL) thickness at 3 months between groups | 3 months | Ganglion cell layer (GCL) thickness at 3 months between groups |
| Other | Ganglion cell layer (GCL) thickness at 6 months between groups | 6 months | Ganglion cell layer (GCL) thickness at 6 months between groups |
Source ClinicalTrials.govtrials-2026-11-12-0.4.0
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNone stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this list from software.
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GET https://conductscience.org/api/trials/v1/NCT06453694/registered?page=2