Trial · NCT06513949
Anti-CD14 Treatment With IC14 in Hospitalized ARDS Patients
NCT06513949, Phase 2, Recruiting, Implicit Bioscience
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. Anti-CD14 Treatment With IC14 in Hospitalized ARDS Patients. Trials, record NCT06513949. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT06513949
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- Anti-CD14 Treatment With IC14 in Hospitalized ARDS Patients
- NCT number
- NCT06513949
- Status
- Recruiting
- Phases
- Phase 2
- Enrollment
- 56 participants, estimated
- Lead sponsor
- Implicit Bioscience
- Conditions
- Acute Respiratory Distress Syndrome, Adult Respiratory Distress Syndrome, Acute Lung Injury, Acute Lung Injury/Acute Respiratory Distress Syndrome (ARDS)
- Interventions
- Atibuclimab, Placebo
- First posted
- 2024-07-22
- Last updated
- 2026-07-29
Source ClinicalTrials.gov
Registered outcomes16
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | Day 4 Oxygenation Index | Day 1 through Day 4 | (mean airway pressure x fraction of inspired oxygen \[FiO2\] x100)/ partial pressure of oxygen \[PaO2\] |
| Secondary | Biomarkers of injury and inflammation measured in bronchoalveolar lavage fluid | Day 4 | Interleukin(IL)-6 |
| Secondary | Biomarkers of injury and inflammation measured in plasma | Day 4 | Interleukin(IL)-6 |
| Secondary | Oxygenation index | Days 7 and 14 | (mean airway pressure x FiO2 x100)/PaO2 |
| Secondary | Oxygen saturation index | Days 4, 7, and 14 | (mean airway pressure x FiO2 x100)/peripheral oxygen saturation \[SpO2\] |
| Secondary | P:F ratio | Days 4, 7, and 14 | Ratio of partial pressure of arterial oxygen (P) to fraction of inspired oxygen (F) |
| Secondary | S:F ratio | Days 4, 7, and 14 | Ratio of the arterial oxygen saturation (S) to fraction of inspired oxygen (F) |
| Secondary | Sequential Organ Failure Assessment (SOFA) Score (range 0 [best] to 24 [worst]) | Days 4, 7, and 14 | Disease severity scale |
| Secondary | Time to blood presepsin level | Days 0-4 | Time from study consent to measurement completion of blood presepsin level via the PATHFASTTM instrument |
| Secondary | Cumulative incidence of run failures | Days 0-1 | Defined as not completing presepsin measurement between consent and infusion of study drug |
1 to 10 of 16Source ClinicalTrials.gov
See all 16 registered outcomesOutcomes0
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
None in this release.
Results by group0
Each measurement the trial posted, group by group, in the words and numbers it posted.
None in this release.
Participant flow0
How many started, completed or left each group, period by period.
None in this release.
Adverse events0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
None in this release.
Adverse event totals0
The totals the trial posted for each group.
None in this release.
Papers0
The papers the trial lists on ClinicalTrials.gov.
None in this release.
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
None in this release.
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT06513949
GET https://conductscience.org/api/trials/v1/NCT06513949/registered