Trial · NCT06527404
A Phase 3, Placebo-controlled, Double-blind Study Assessing Rocatinlimab in Prurigo Nodularis
NCT06527404, Phase 3, Terminated, Amgen
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. A Phase 3, Placebo-controlled, Double-blind Study Assessing Rocatinlimab in Prurigo Nodularis. Trials, record NCT06527404. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT06527404
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- A Phase 3, Placebo-controlled, Double-blind Study Assessing Rocatinlimab in Prurigo Nodularis
- NCT number
- NCT06527404
- Status
- Terminated
- Phases
- Phase 3
- Enrollment
- 469 participants, actual
- Lead sponsor
- Amgen
- Conditions
- Prurigo Nodularis
- Interventions
- Rocatinlimab, Placebo
- First posted
- 2024-07-30
- Last updated
- 2026-07-27
Source ClinicalTrials.gov
Registered outcomes24
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | Global: Number of Participants Achieving Reduction from Baseline in Weekly Average of Daily Itch Score at Week 24 | Up to 24 weeks | |
| Primary | US Only: Number of Participants Achieving Reduction from Baseline in Weekly Average of Daily Itch Score and Prurigo Nodularis Stage Assessment at Week 24 | Up to 24 weeks | |
| Secondary | Global: Number of Participants Achieving Improvement in Prurigo Nodularis Stage Assessment Score at Week 24 | Week 24 | |
| Secondary | Global: Number of Participants Achieving Reduction from Baseline in Weekly Average of Daily Itch Score and Prurigo Nodularis Stage Assessment at Week 24 | Baseline and Week 24 | |
| Secondary | Global: Percentage Improvement from Baseline in Weekly Average of Daily Itch Score at Week 24 | Baseline and Week 24 | |
| Secondary | Global: Number of Participants Achieving Reduction in Weekly Average Daily Prurigo Nodularis Skin Pain Assessment at Week 24 in Those with Baseline NRS Above Cutoff | Baseline and Week 24 | |
| Secondary | US Only: Number of Participants Achieving Reduction from Baseline in Weekly Average of Daily Itch Score at Week 24 | Baseline and Week 24 | |
| Secondary | US Only: Number of Participants with Improvement in Prurigo Nodularis Stage Assessment at Week 24 | Week 24 | |
| Secondary | US Only: Percent Improvement from Baseline in Weekly Average of Daily Itch Score at Week 24 | Week 24 | |
| Secondary | US Only: Number of Participants Achieving Reduction from Baseline in Weekly Average of Daily Skin Pain Assessment at Week 24 in Participants With Baseline Score Greater Than or Equal to a Cutoff Score | Week 24 |
1 to 10 of 24Source ClinicalTrials.gov
See all 24 registered outcomesOutcomes0
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
None in this release.
Results by group0
Each measurement the trial posted, group by group, in the words and numbers it posted.
None in this release.
Participant flow0
How many started, completed or left each group, period by period.
None in this release.
Adverse events0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
None in this release.
Adverse event totals0
The totals the trial posted for each group.
None in this release.
Papers0
The papers the trial lists on ClinicalTrials.gov.
None in this release.
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
None in this release.
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT06527404
GET https://conductscience.org/api/trials/v1/NCT06527404/registered?page=2