Effects of Oral Nicotine and Caffeine Pouches on Anaerobic Performance, Autonomic Function, Cognition, and Behavior
NCT06529055, Not applicable, Unknown, University of Southern Mississippi
Trial 10
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
| Field | Value | Source |
|---|---|---|
| Title | Effects of Oral Nicotine and Caffeine Pouches on Anaerobic Performance, Autonomic Function, Cognition, and Behavior | ClinicalTrials.gov |
| NCT number | NCT06529055 | ClinicalTrials.gov |
| Status | Unknown | ClinicalTrials.gov |
| Phases | Not applicable | ClinicalTrials.gov |
| Enrollment | 20 participants, estimated | ClinicalTrials.gov |
| Lead sponsor | University of Southern Mississippi | ClinicalTrials.gov |
| Conditions | Fatigue; Muscle, Heart, Fatigue, Mental | ClinicalTrials.gov |
| Interventions | Oral Pouch - Nicotine, Oral Pouch - Caffeine, Oral Pouch - Placebo | ClinicalTrials.gov |
| First posted | 2024-07-31 | ClinicalTrials.gov |
| Last updated | 2024-08-02 | ClinicalTrials.gov |
Registered outcomes 27
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description | Source |
|---|---|---|---|---|
| Primary | Wingate Anaerobic Cycling Test | Baseline, 15, 16, 19, 20, 23, 24, 27, 28, 31, 32, and 60 minutes post-ingestion | Changes in anaerobic cycling power output | ClinicalTrials.gov |
| Primary | Concentration of blood lactate | Baseline, 25, 32 minutes post-ingestion | Changes in blood lactate concentration from capillary blood | ClinicalTrials.gov |
| Primary | Concentration of salivary cortisol | Baseline, 15, 25, 32 minutes post-ingestion | Changes in salivary cortisol concentration from saliva | ClinicalTrials.gov |
| Primary | Concentration of salivary interleukin-6 | Baseline, 15, 25, 32 minutes post-ingestion | Changes in interleukin-6 concentration from saliva | ClinicalTrials.gov |
| Primary | Salivary catecholamine concentration | Baseline, 15, 27, 40 minutes post-ingestion | Changes in salivary catecholamine concentration from saliva | ClinicalTrials.gov |
| Primary | Profile of Mood States | Baseline, 15, 32 minutes post-ingestion | Changes in Profile of Mood States scores (Score range: 0-60) | ClinicalTrials.gov |
| Primary | Balance | Baseline, 15, 32 minutes post-ingestion | Changes in standing postural sway | ClinicalTrials.gov |
| Primary | Ratings of perceived exertion | Baseline, 15, 16, 19, 20, 23, 24, 27, 28, 31, 32, and 60 minutes post-ingestion | Changes in ratings of perceived exertion (Scale range: 6-20 - lower ratings means less effort)) | ClinicalTrials.gov |
| Primary | Hunger - Visual Digital Analog Scale (0-100) | Baseline, 15, 25, 32 minutes post-ingestion | Changes in subjective ratings of hunger | ClinicalTrials.gov |
| Primary | Desire to eat - Visual Digital Analog Scale (0-100) | Baseline, 15, 25, 32, 60 minutes post-ingestion | Changes in subjective ratings of desire to eat | ClinicalTrials.gov |
| Primary | Prospective Consumption of Food - Visual Digital Analog Scale (0-100) | Baseline, 15, 25, 32, 60 minutes post-ingestion | Changes in subjective ratings of prospective consumption of food | ClinicalTrials.gov |
| Primary | Fullness - Visual Digital Analog Scale (0-100) | Baseline, 15, 25, 32, 60 minutes post-ingestion | Changes in subjective ratings of fullness | ClinicalTrials.gov |
| Primary | Food Intake - Digital 24-hour food record | 24 hours following the end of each visit | Consumption of food and beverage after study visit | ClinicalTrials.gov |
| Primary | Blood Pressure | Baseline, 15, 19, 23, 27, 31, and 60 minutes post-ingestion | Absolute brachial blood pressure values (systolic and diastolic) and relative changes from baseline. | ClinicalTrials.gov |
| Primary | Heart Rate | Baseline, 15, 19, 23, 27, 31, and 60 minutes post-ingestion | Absolute heart rate values and relative changes from baseline. | ClinicalTrials.gov |
| Primary | Trail Making Test - Digital Cognitive Function Test | Baseline, 15, 32 minutes post-ingestion | Changes in trail making test scores | ClinicalTrials.gov |
| Primary | Sustained Attention Test - Digital Cognitive Function Test | Baseline, 15, 32 minutes post-ingestion | Changes in sustained attention test scores | ClinicalTrials.gov |
| Primary | Visual Working Memory Span Test - Digital Cognitive Function Test | Baseline, 15, 32 minutes post-ingestion | Changes in visual working memory span test scores | ClinicalTrials.gov |
| Primary | Stroop Test - Digital Cognitive Function Test | Baseline, 15, 32 minutes post-ingestion | Changes in Stroop test scores | ClinicalTrials.gov |
| Primary | Deary-Liewald Test - Digital Cognitive Function Test | Baseline, 15, 32 minutes post-ingestion | Changes in Deary-Liewald test scores | ClinicalTrials.gov |
Outcomes 0
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
| Type | Outcome | Time frame | Population | Units | Measured as | Source |
|---|
Results by group 0
Each measurement the trial posted, group by group, in the words and numbers it posted.
| Outcome | Group | Category | Value | Spread | Units | Source |
|---|
Participant flow 0
How many started, completed or left each group, period by period.
| Period | Milestone | Group | Participants | Units counted | Source |
|---|
Adverse events 0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
| Type | Event | Organ system | Group | Affected | At risk | Events | Source |
|---|
Adverse event totals 0
The totals the trial posted for each group.
| Total | Group | Affected | At risk | Source |
|---|
Papers 0
The papers the trial lists on ClinicalTrials.gov.
| PMID | Listed as | Source |
|---|
Grants 0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
| Project | Title | Principal investigators | Organization | Funder | Fiscal years | Source |
|---|
Trial comparisons 0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
| Comparison | Source |
|---|
Tests 3
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
| Test | Named as | Source |
|---|---|---|
| Stroop Color-Word Test | Primary outcome | ConductCognition |
| Trail Making Test A | Primary outcome | ConductCognition |
| Trail Making Test B | Primary outcome | ConductCognition |
Source 5
| Field | Value | Source |
|---|---|---|
| Release | trials-2026-11-12-0.4.0 | ClinicalTrials.gov |
| Release manifest SHA-256 | 0f4a8d8c48aee2a7573ae0fa94ecbeab70c1adbe449bbc95c424bc7d3e97b9d4 | ClinicalTrials.gov |
| Registry capture | 2026-11-12 | ClinicalTrials.gov |
| Results copy, AACT | 2026-03-23 | ClinicalTrials.gov |
| NIH clinical studies file | 2026-11-13 | ClinicalTrials.gov |
Release trials-2026-11-12-0.4.0
ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
NIH RePORTER's clinical studies and project files: Public domain (NIH RePORTER)