Trial · NCT06540963
Tipifarnib and Naxitamab for Relapsed/Refractory Neuroblastoma
NCT06540963, Phase 2, Recruiting, Giselle Sholler
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. Tipifarnib and Naxitamab for Relapsed/Refractory Neuroblastoma. Trials, record NCT06540963. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT06540963
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- Tipifarnib and Naxitamab for Relapsed/Refractory Neuroblastoma
- NCT number
- NCT06540963
- Status
- Recruiting
- Phases
- Phase 2
- Enrollment
- 98 participants, estimated
- Lead sponsor
- Giselle Sholler
- Conditions
- Neuroblastoma
- Interventions
- Tipifarnib, Naxitamab
- First posted
- 2024-08-07
- Last updated
- 2026-09-03
Source ClinicalTrials.gov
Registered outcomes4
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | Determine the Overall Response Rate (ORR) of Participants using INSS Response | 6 months | To evaluate the activity of Tipifarnib in combination with Naxitamab based on Overall response rate (ORR) |
| Secondary | Number of participants with progression free survival (PFS) during study | 6 months plus 5 years follow up | To evaluate the activity of Tipifarnib in combination with Naxitamab based on Progression free survival (PFS) |
| Secondary | Length of time that participants experience Overall Survival (OS) | 6 months plus 5 years follow up | To evaluate the efficacy of Tipifarnib in combination with Naxitamab based upon Overall Survival (OS) |
| Secondary | Number of Participants with Adverse Events as a Measure of Safety and Tolerability | 6 months plus 30 days | To evaluate the safety and tolerability profile of Tipifarnib in combination with Naxitamab in pediatric and young adult participants. |
Source ClinicalTrials.gov
Outcomes0
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
None in this release.
Results by group0
Each measurement the trial posted, group by group, in the words and numbers it posted.
None in this release.
Participant flow0
How many started, completed or left each group, period by period.
None in this release.
Adverse events0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
None in this release.
Adverse event totals0
The totals the trial posted for each group.
None in this release.
Papers0
The papers the trial lists on ClinicalTrials.gov.
None in this release.
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
None in this release.
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT06540963
GET https://conductscience.org/api/trials/v1/NCT06540963/registered