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Trial · NCT06547112

A Pharmacodynamic Study of the Apheresis Product of Multiple Myeloma Patients Undergoing Quad-induction Followed by Motixafortide + G-CSF Mobilization

NCT06547112, Phase 1, Completed, Washington University School of Medicine

3 sourcestrials-2026-11-12-0.5.0

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ConductScience Library. A Pharmacodynamic Study of the Apheresis Product of Multiple Myeloma Patients Undergoing Quad-induction Followed by Motixafortide + G-CSF Mobilization. Trials, record NCT06547112. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT06547112

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Trial

As registered on ClinicalTrials.gov, in the graph's capture of the registry.

Title
A Pharmacodynamic Study of the Apheresis Product of Multiple Myeloma Patients Undergoing Quad-induction Followed by Motixafortide + G-CSF Mobilization
NCT number
NCT06547112
Status
Completed
Phases
Phase 1
Enrollment
20 participants, actual
Lead sponsor
Washington University School of Medicine
Conditions
Multiple Myeloma
Interventions
Motixafortide, G-CSF
First posted
2024-08-09
Last updated
2025-08-29

Source ClinicalTrials.gov

Registered outcomes17

Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.

ListOutcomeTime frameDescription
PrimaryAbsolute number and relative proportions of CD34+ cell subsets by extended immunophenotypic profiling using multicolor fluorescence activated cell sorting (mFACS) on the apheresis productFrom day 5 through day 8 (up to 4 days)
SecondaryNumber of participants with adverse eventsFrom day 4 to end of study visit (estimated to be 15-26 days)
SecondaryChange in concomitant medication useFrom baseline through end of study visit (estimated to be 15-26 days)
SecondaryTreatment complianceFrom day 4 to end of study visit (estimated to be 15-26 days)
SecondaryNumber of participants who dropout due to adverse eventsFrom day 4 to end of study visit (estimated to be 15-26 days)
SecondaryChange in blood pressureFrom baseline through end of study visit (estimated to be 15-26 days)
SecondaryChange in temperatureFrom baseline through end of study visit (estimated to be 15-26 days)
SecondaryChange in heart rateFrom baseline through end of study visit (estimated to be 15-26 days)
SecondaryChange in respiratory rateFrom baseline through end of study visit (estimated to be 15-26 days)
SecondaryChange in oxygen saturation at room airFrom baseline through end of study visit (estimated to be 15-26 days)

Outcomes0

Each outcome the trial posted results for, in ClinicalTrials.gov's words.

None in this release.

Results by group0

Each measurement the trial posted, group by group, in the words and numbers it posted.

None in this release.

Participant flow0

How many started, completed or left each group, period by period.

None in this release.

Adverse events0

Each adverse event the trial posted, group by group: the participants affected out of those at risk.

None in this release.

Adverse event totals0

The totals the trial posted for each group.

None in this release.

Papers0

The papers the trial lists on ClinicalTrials.gov.

None in this release.

Grants0

The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.

None in this release.

Trial comparisons0

Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.

None in this release.

Tests0

The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.

None in this release.

Data dates

The day each source was copied for this release.

ClinicalTrials.gov
2026-11-12
ClinicalTrials.gov
Results, from AACT
2026-03-23
AACT
NIH grant links
2026-11-13
NIH RePORTER

Sources 3

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ClinicalTrials.govNo license stated
  • NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ClinicalTrials.govnone stated
  • NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this trial from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/trials/v1/NCT06547112

GET https://conductscience.org/api/trials/v1/NCT06547112/registered