Trial · NCT06554717
Tesamorelin as an Adjunct to Exercise for Improving Physical Function in HIV
NCT06554717, Phase 2, Recruiting, Massachusetts General Hospital
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. Tesamorelin as an Adjunct to Exercise for Improving Physical Function in HIV. Trials, record NCT06554717. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT06554717
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- Tesamorelin as an Adjunct to Exercise for Improving Physical Function in HIV
- NCT number
- NCT06554717
- Status
- Recruiting
- Phases
- Phase 2
- Enrollment
- 100 participants, estimated
- Lead sponsor
- Massachusetts General Hospital
- Conditions
- HIV-1-infection, Frailty, Impaired Physical Function, Abdominal Obesity, Aging
- Interventions
- Tesamorelin, Placebo, Exercise
- First posted
- 2024-08-15
- Last updated
- 2026-05-19
Source ClinicalTrials.gov
Registered outcomes12
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | Change in Repeated Chair Stand Time | Baseline to Week 24 | Time to complete 10 repeated chair stands |
| Secondary | Change in Standard and Modified Short Physical Performance Battery (SPPB) | Baseline to Week 24 | Objective assessment of physical function that includes measures of balance, gait, and strength |
| Secondary | Change in 1-Repetition Maximum Leg Press | Baseline to Week 24 | Maximal weight that can be lifted by lower extremities once using correct form through full range of motion |
| Secondary | Change in 400-Meter Walk Time | Baseline to Week 24 | Time to walk 400 meters at the fastest pace possible |
| Secondary | Change in Appendicular Lean Tissue Mass | Baseline to Week 24 | Dual-energy x-ray absorptiometry (DXA) lean tissue mass in all four extremities |
| Secondary | Change in Cross-Sectional Area of Trunk and Thigh Muscles | Baseline to Week 24 | Computed tomography (CT) cross-sectional area of trunk and thigh muscles |
| Secondary | Change in Frailty Phenotype | Baseline to Week 24 | Fried Frailty Phenotype score, scored from 0 to 5 with higher indicating worse |
| Secondary | Change in Quality of Life | Baseline to Week 24 | 36-Item Short Form Health Survey (SF-36), scored from 0 to 100 with higher indicating better |
| Secondary | Change in Exercise Self-Efficacy | Baseline to Week 24 | Exercise Self-Efficacy Scale, scored from 0 to 100 with higher indicating better |
| Secondary | Change in Exercise Adherence | Baseline to Week 24 | FitBit (step count heart rate time), exercise log (movement type, repetitions, load, rate of perceived exertion) |
1 to 10 of 12Source ClinicalTrials.gov
See all 12 registered outcomesOutcomes0
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
None in this release.
Results by group0
Each measurement the trial posted, group by group, in the words and numbers it posted.
None in this release.
Participant flow0
How many started, completed or left each group, period by period.
None in this release.
Adverse events0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
None in this release.
Adverse event totals0
The totals the trial posted for each group.
None in this release.
Papers1
The papers the trial lists on ClinicalTrials.gov.
| PMID | Listed as |
|---|---|
| 42419889 | DERIVED |
Source PubMed
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
None in this release.
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT06554717
GET https://conductscience.org/api/trials/v1/NCT06554717/registered