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Trial · NCT06603727

Computerized Cognitive Rehabilitation of Patients With Cognitive Deficits Due to the Human Immunodeficiency Virus

NCT06603727, Not applicable, Unknown, Centre Hospitalier Universitaire Vaudois

3 sourcestrials-2026-11-12-0.5.0

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ConductScience Library. Computerized Cognitive Rehabilitation of Patients With Cognitive Deficits Due to the Human Immunodeficiency Virus. Trials, record NCT06603727. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT06603727

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Trial

As registered on ClinicalTrials.gov, in the graph's capture of the registry.

Title
Computerized Cognitive Rehabilitation of Patients With Cognitive Deficits Due to the Human Immunodeficiency Virus
NCT number
NCT06603727
Status
Unknown
Phases
Not applicable
Enrollment
24 participants, estimated
Lead sponsor
Centre Hospitalier Universitaire Vaudois
Conditions
Human Immunodeficiency Virus, Cognitive Dysfunction
Interventions
Computerized Gaming Rehabilitation Program 1, Computerized Gaming Rehabilitation Program 2
First posted
2024-09-19
Last updated
2024-09-19

Source ClinicalTrials.gov

Registered outcomes37

Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.

ListOutcomeTime frameDescription
PrimaryChange in subjective everyday life cognition after a 6 weeks period of gamified cognitive and physical training (program 1 vs program 2)6 weeks
Subjective executive function is measured by the Working Memory Questionnaire (WMQ), a 30-item, self-administered scale (score range from 0 to 120), addressing working memory (10 items), attention (10 items) and general executive function (10 items). The higher the score, the more it reflects cognitive difficulties.
PrimaryChange in speed of information processing after a 6 weeks period of gamified cognitive and physical training6 weeksMeasured by the Symbol Digit Modalities Test (SDMT), scored from 0 to 110. The lower the score, the more it reflects cognitive difficulties.
PrimaryChange in cognitive flexibility after a 6 weeks period of cognitive and physical training (program 1 vs program 2)6 weeks
Measured by the time completion of the Color Trails Test (CTT) in CTT1 and CTT2 (i.e., Flexibility Index: (CTT2-CTT1)/CTT1). The higher the Flexibility Index, the more it reflects cognitive difficulties.
PrimaryChange in visuospatial short-term memory after a 6 weeks period of cognitive and physical training (program 1 vs program 2)6 weeksMeasured by the Brief Visuospatial Memory Test-Revised (BVMT-R), scored from 0 to 36. The lower the score, the more it reflects cognitive difficulties.
SecondaryChange in sustained attention after a 6 weeks period of gamified cognitive and physical training (program 1 vs program 2)6 weeksMeasured with the Test of Variables of Attention (TOVA) using the reaction time (RT) and the false alarm rate (FA). The higher the RT and FA, the more they reflect cognitive difficulties.
SecondaryChange in cognitive interference after a 6 weeks period of gamified cognitive and physical training (program 1 vs program 2)6 weeksMeasured with the Denis-Kaplan Color-Word interference Stroop test using the time completion in each condition. The higher the time completion, the more it reflects cognitive difficulties.
SecondaryChange in design fluency after a 6 weeks period of gamified cognitive and physical training (program 1 vs program 2)6 weeksThe Five-Point Test will be used to assess design fluency using the total number of design produced. The lower the score, the more it reflects cognitive difficulties.
SecondaryChange in cognitive flexibility after a 6 weeks period of gamified cognitive and physical training (program 1 vs program 2)6 weeksA subtest of a custom-made tablet-based cognitive evaluation tool will measure cognitive flexibility.
SecondaryChange in visuo-spatial and verbal working memory control after a 6 weeks period of gamified cognitive and physical training (program 1 vs program 2)6 weeksMeasured using the Digit and Visuo-Spatial Span Test
SecondaryChange in divided attention after a 6 weeks period of gamified cognitive and physical training (program 1 vs program 2)6 weeksMeasured using the Test of Attentional Performance subtest Divided Attention

Outcomes0

Each outcome the trial posted results for, in ClinicalTrials.gov's words.

None in this release.

Results by group0

Each measurement the trial posted, group by group, in the words and numbers it posted.

None in this release.

Participant flow0

How many started, completed or left each group, period by period.

None in this release.

Adverse events0

Each adverse event the trial posted, group by group: the participants affected out of those at risk.

None in this release.

Adverse event totals0

The totals the trial posted for each group.

None in this release.

Papers23

The papers the trial lists on ClinicalTrials.gov.

PMIDListed asSource
5939936BACKGROUNDPubMed
7126941BACKGROUNDPubMed
7162920BACKGROUNDPubMed
8180914BACKGROUNDPubMed
9330549BACKGROUNDPubMed
9881538BACKGROUNDPubMed
10960937BACKGROUNDPubMed
12422327BACKGROUNDPubMed
14589670BACKGROUNDPubMed
15012851BACKGROUNDPubMed

1 to 10 of 23

See all 23 papers

Grants0

The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.

None in this release.

Trial comparisons0

Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.

None in this release.

Tests3

The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.

TestNamed asSource
Symbol CodingPrimary outcomeConductCognition
Design Fluency TestSecondary outcomeConductCognition
Stroop Color-Word TestSecondary outcomeConductCognition

Data dates

The day each source was copied for this release.

ClinicalTrials.gov
2026-11-12
ClinicalTrials.gov
Results, from AACT
2026-03-23
AACT
NIH grant links
2026-11-13
NIH RePORTER

Sources 3

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ClinicalTrials.govNo license stated
  • NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ClinicalTrials.govnone stated
  • NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this trial from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/trials/v1/NCT06603727

GET https://conductscience.org/api/trials/v1/NCT06603727/registered?page=2