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Trial · NCT06609343

Bupropion for Fatigue in End-stage Kidney Disease Patients on Hemodialysis

NCT06609343, Phase 1, Phase 2, Not yet recruiting, The University of Texas Health Science Center at San Antonio

3 sourcestrials-2026-11-12-0.5.0

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ConductScience Library. Bupropion for Fatigue in End-stage Kidney Disease Patients on Hemodialysis. Trials, record NCT06609343. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT06609343

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Trial

As registered on ClinicalTrials.gov, in the graph's capture of the registry.

Title
Bupropion for Fatigue in End-stage Kidney Disease Patients on Hemodialysis
NCT number
NCT06609343
Status
Not yet recruiting
Phases
Phase 1, Phase 2
Enrollment
16 participants, estimated
Lead sponsor
The University of Texas Health Science Center at San Antonio
Conditions
End Stage Renal Disease, Fatigue
Interventions
Bupropion Hydrochloride 150 MG
First posted
2024-09-24
Last updated
2026-11-02

Source ClinicalTrials.gov

Registered outcomes5

Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.

ListOutcomeTime frameDescription
PrimaryChange in Brief Fatigue Inventory (BFI) Global ScoreBaseline to 8 weeksThis inventory contains 9 items scored from 0-10 with a total possible raw score of 0-90. A lower score indicates that there is less fatigue
SecondaryChange in plasma concentration of inflammatory marker IL-6Baseline to 8 weeksPlasma level of inflammatory marker of interleukin-6 (IL-6)
SecondaryChange in plasma concentration of inflammatory marker TNF-αBaseline to 8 weeksPlasma level of tumor necrosis factor-alpha (TNF-α)
OtherChange in Cognitive function using Trail Making Test BBaseline to 8 weeks
The participant will need a pencil to perform each part. The examiner starts timing as soon as the instructions are completed and the participant is signaled to begin. Timing is continued until the participant completes or discontinues the test. The time to completion in seconds is recorded. The maximum score for Part B is 300 seconds with 301" indicating the test was discontinued. A lower score indicates that the participant has better cognitive function and completed the task faster.
OtherChange in Mini-COG scoreBaseline to 8 weeks
The score is made up of 2 parts: recall score is 0-3 points, 1 point is assigned for each word correctly recalled without prompt, so the score is higher if more words are recalled. For the clock drawing score, the possible score is 0-2 points, a higher score indicates more accuracy. The total score is between 0-5 with a higher score indicating better cognitive function.

Outcomes0

Each outcome the trial posted results for, in ClinicalTrials.gov's words.

None in this release.

Results by group0

Each measurement the trial posted, group by group, in the words and numbers it posted.

None in this release.

Participant flow0

How many started, completed or left each group, period by period.

None in this release.

Adverse events0

Each adverse event the trial posted, group by group: the participants affected out of those at risk.

None in this release.

Adverse event totals0

The totals the trial posted for each group.

None in this release.

Papers0

The papers the trial lists on ClinicalTrials.gov.

None in this release.

Grants0

The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.

None in this release.

Trial comparisons0

Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.

None in this release.

Tests3

The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.

TestNamed asSource
Clock Drawing TaskOther outcomeConductCognition
Trail Making Test AOther outcomeConductCognition
Trail Making Test BOther outcomeConductCognition

Data dates

The day each source was copied for this release.

ClinicalTrials.gov
2026-11-12
ClinicalTrials.gov
Results, from AACT
2026-03-23
AACT
NIH grant links
2026-11-13
NIH RePORTER

Sources 3

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ClinicalTrials.govNo license stated
  • NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ClinicalTrials.govnone stated
  • NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this trial from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/trials/v1/NCT06609343

GET https://conductscience.org/api/trials/v1/NCT06609343/registered