Registered outcomes11

Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.

1 to 11 of 11

List	Outcome	Time frame	Description
Primary	Number of adjudicated Vaso-occlusive crisis (VOC) events with a medical contact	Baseline (week 0) to week 52	Measured as Count of events.
Secondary	Change in Haemoglobin (Hb) greater than 1 grams per decilitre (g/dL)	Baseline (week 0) to week 24	Measured in Count of participants.
Secondary	Time to onset of first adjudicated Vaso-occlusive crisis (VOC)	Baseline (week 0) to week 52	Measured as time in days.
Secondary	Change in standardised T-score on the Patient-Reported Outcomes Measurement Information System (PROMIS) Fatigue 7a Scale	Baseline (week 0) to week 52	Measured in T-score.
Secondary	Change in haemoglobin (Hb)	Baseline (week 0) to week 52	Measured in grams per decilitre (g/dL).
Secondary	Change in lactate dehydrogenase (LDH)	Baseline (week 0) to week 52	Measured in Units per litre (U/L).
Secondary	Change in absolute reticulocyte count	Baseline (week 0) to week 52	Measured as Cells x10\^9/L.
Secondary	Change in indirect bilirubin	Baseline (week 0) to week 52	Measured in milligrams per decilitre (mg/dL).
Secondary	Change in distance travelled during the 6-minute walking test (6MWT)	Baseline (week 0) to week 52	Measured in Meters.
Secondary	Participants achieving the threshold for clinically meaningful change (yes/no) in PROMIS fatigue scale 7a	Baseline (week 0) to week 52	Measured as Count of participants.
Secondary	Participants achieving the threshold for clinically meaningful change (yes/no) in 6MWT	Baseline (week 0) to week 52	Measured as Count of participants.

Source ClinicalTrials.govtrials-2026-11-12-0.5.0

Sources 3

ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
ClinicalTrials.govNo license stated
NIH RePORTER's clinical studies and project filesPublic domain

Each source's terms

ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
ClinicalTrials.govnone stated
NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Twenty rows a page, as JSON. No key.

GET https://conductscience.org/api/trials/v1/NCT06612268/registered