Trial · NCT06615102
Reducing Cardiac-surgery Associated Acute Kidney Injury Occurence by Administering Angiotensin II
NCT06615102, Phase 3, Recruiting, Universität Münster
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. Reducing Cardiac-surgery Associated Acute Kidney Injury Occurence by Administering Angiotensin II. Trials, record NCT06615102. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT06615102
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- Reducing Cardiac-surgery Associated Acute Kidney Injury Occurence by Administering Angiotensin II
- NCT number
- NCT06615102
- Status
- Recruiting
- Phases
- Phase 3
- Enrollment
- 1,022 participants, estimated
- Lead sponsor
- Universität Münster
- Conditions
- Cardiac Surgery, Vasoplegia
- Interventions
- Angiotensin II, Noradrenalin
- First posted
- 2024-09-26
- Last updated
- 2025-07-18
Source ClinicalTrials.gov
Registered outcomes29
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | Rate of AKI KDIGO stage 2 or 3 or death within 72 hours after end of cardiac surgery. | 72 hours after end of surgery | |
| Secondary | Major Adverse Kidney Events (MAKE90) | 90 after cardiac surgery | 1\. MAKE90 (consisting of mortality, dialysis within 90 days, persistent renal dysfunction (defined as serum creatinine ≥ 2x compared to baseline value at day 90) |
| Secondary | Severity of Acute Kidney Injury | 72 hours after cardiac surgery | Number of patients with KDIGO stage 1, KDIGO stage 2 or KDIGO stage 3) |
| Secondary | Development or progression of chronic kidney injury | 90 to 120 days after cardiac surgery | Development or progression of chronic kidney disease based on albuminuria, urine creatinine (and the respective ratio) and serum creatinine or death within 120 days |
| Other | Use of additional open-label vasopressors or inotropes | within 72 h after cardiac surgery | |
| Other | Volume of fluid application within the first 72 hours | within 72 h after cardiac surgery | |
| Other | Volume status | within 72 h after cardiac surgery | |
| Other | Time to death | 30 days after cardiac surgery | |
| Other | Time to death | 60 days after cardiac surgery | |
| Other | Time to death | 90 days after cardiac surgery |
1 to 10 of 29Source ClinicalTrials.gov
See all 29 registered outcomesOutcomes0
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
None in this release.
Results by group0
Each measurement the trial posted, group by group, in the words and numbers it posted.
None in this release.
Participant flow0
How many started, completed or left each group, period by period.
None in this release.
Adverse events0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
None in this release.
Adverse event totals0
The totals the trial posted for each group.
None in this release.
Papers0
The papers the trial lists on ClinicalTrials.gov.
None in this release.
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
None in this release.
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT06615102
GET https://conductscience.org/api/trials/v1/NCT06615102/registered?page=2