Trial · NCT06638671
Short-Term Metformin Use in Young, Healthy Adults: Impacts on Exercise Capacity
NCT06638671, Phase 4, Completed, University of Virginia
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. Short-Term Metformin Use in Young, Healthy Adults: Impacts on Exercise Capacity. Trials, record NCT06638671. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT06638671
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- Short-Term Metformin Use in Young, Healthy Adults: Impacts on Exercise Capacity
- NCT number
- NCT06638671
- Status
- Completed
- Phases
- Phase 4
- Enrollment
- 14 participants, actual
- Lead sponsor
- University of Virginia
- Conditions
- Exercise Capacity, Metformin
- Interventions
- Metformin Hydrochloride, Placebo
- First posted
- 2024-10-15
- Last updated
- 2026-06-17
Source ClinicalTrials.gov
Registered outcomes13
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | Exercise capacity | 6 weeks | Exercise capacity will be measured by absolute and relative VO2peak |
| Primary | Lactate threshold | 6 weeks | Lactate threshold (LT) will be determined by power output immediately before the curvilinear increase in lactate concentration |
| Primary | VO2 at Lactate threshold | 6 weeks | VO2 at LT denoted as VO2 obtained at the same power output as LT |
| Primary | Lactate turnpoint (LTP) | 6 weeks | LTP will be determined by the power output obtained immediately before the second sharp increase in blood lactate concentration |
| Primary | Maximal power output | 6 weeks | Maximal power output (watts) during exercise |
| Secondary | Respiratory exchange ratio (RER) | 6 weeks | RER will be determined during exercise as the ratio of expired CO2 and inspired O2, as an estimate of substrate utilization |
| Secondary | Ventilation (VE) | 6 weeks | Minute ventilation collected during exercise |
| Secondary | Maximal fat oxidation (Fatmax) | 6 weeks | Maximal amount of fat oxidized during exercise |
| Other | Resting blood pressure | 6 weeks | Blood pressure obtained before exercise in a resting state |
| Other | Blood pressure during exercise | 6 weeks | Blood pressure measured during exercise at end of each stage |
1 to 10 of 13Source ClinicalTrials.gov
See all 13 registered outcomesOutcomes0
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
None in this release.
Results by group0
Each measurement the trial posted, group by group, in the words and numbers it posted.
None in this release.
Participant flow0
How many started, completed or left each group, period by period.
None in this release.
Adverse events0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
None in this release.
Adverse event totals0
The totals the trial posted for each group.
None in this release.
Papers0
The papers the trial lists on ClinicalTrials.gov.
None in this release.
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
None in this release.
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT06638671
GET https://conductscience.org/api/trials/v1/NCT06638671/registered