Use of Transcranial Magnetic Stimulation in the Post-Operative Cognitive Dysfunction in Elderly
NCT06658769, Not applicable, Recruiting, University of Sao Paulo General Hospital
Trial 10
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
| Field | Value | Source |
|---|---|---|
| Title | Use of Transcranial Magnetic Stimulation in the Post-Operative Cognitive Dysfunction in Elderly | ClinicalTrials.gov |
| NCT number | NCT06658769 | ClinicalTrials.gov |
| Status | Recruiting | ClinicalTrials.gov |
| Phases | Not applicable | ClinicalTrials.gov |
| Enrollment | 12 participants, estimated | ClinicalTrials.gov |
| Lead sponsor | University of Sao Paulo General Hospital | ClinicalTrials.gov |
| Conditions | Postoperative Cognitive Dysfunction | ClinicalTrials.gov |
| Interventions | Theta Burst Stimulation, Theta Burst Stimulation Sham | ClinicalTrials.gov |
| First posted | 2024-10-26 | ClinicalTrials.gov |
| Last updated | 2024-10-26 | ClinicalTrials.gov |
Registered outcomes 4
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description | Source |
|---|---|---|---|---|
| Primary | Changes in Verbal Learning | 1st evaluation: Baseline. 2nd evaluation: 2 days after the application of the active or sham iTBS protocol. 3rd evaluation: 15 days after surgery (surgical groups) or 20 days after the second evaluation (non-surgical group). 4th evaluation: 3 months afte | Hopkins Verbal Learning Test (HVLT) - This test consists of a list of 12 words. After the examiner reads the list, the patient is asked to repeat as many words as possible in any order. This procedure is repeated two more times, and after 25 minutes, a delayed recall is requested. The score is based on the number of words recalled in the delayed recall. | ClinicalTrials.gov |
| Primary | Changes in Attention and Executive Function: | 1st evaluation: Baseline. 2nd evaluation: 2 days after the application of the active or sham iTBS protocol. 3rd evaluation: 15 days after surgery (surgical groups) or 20 days after the second evaluation (non-surgical group). 4th evaluation: 3 months afte | Trail Making Test (A and B) - The test is divided into two parts: the first part (TMT A) involves simple visual search and motor speed, while the second part (TMT B) requires complex visual search due to the alternation of stimuli, thus assessing executive function performance. In part A, the person must connect numbered circles in ascending order. In part B, they must draw lines alternating between numbers in ascending order and letters in alphabetical order. The test evaluates not only selective and alternating attention but also complex visual tracking and motor dexterity (Part A) as well as executive processes (Part B). The time spent and the number of errors made in each part are assessed. | ClinicalTrials.gov |
| Primary | Changes in Attention and Processing Speed | 1st evaluation: Baseline. 2nd evaluation: 2 days after the application of the active or sham iTBS protocol. 3rd evaluation: 15 days after surgery (surgical groups) or 20 days after the second evaluation (non-surgical group). 4th evaluation: 3 months afte | Stroop Test - The Stroop test assesses selective attention, the ability to maintain focus on a task, and the inhibition of the tendency to provide impulsive responses, as well as the speed of information processing. In this task, 99 trials are presented on a computer, featuring the words "green," "red," and "blue," displayed in their respective colors (or not). It measures the response time to name the colors of words that are colored in their actual color (congruent trials) or to state the colors of words with different colors (incongruent trials). It also evaluates the number of correct responses in the trials. Data will be synchronized using MATLAB software. | ClinicalTrials.gov |
| Primary | Changes in Motor Skills | 1st evaluation: Baseline. 2nd evaluation: 2 days after the application of the active or sham iTBS protocol. 3rd evaluation: 15 days after surgery (surgical groups) or 20 days after the second evaluation (non-surgical group). 4th evaluation: 3 months afte | The Grooved Pegboard Test - This is a manual dexterity test consisting of a board with 25 holes of the same shape (similar to a keyhole) and size, but arranged in a random orientation, along with small pegs that must be placed into the holes following a predetermined order, using only one hand. The raw data corresponds to the time taken to complete the task, measured in seconds. The dominant hand is tested first, followed by the non-dominant hand. | ClinicalTrials.gov |
Outcomes 0
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
| Type | Outcome | Time frame | Population | Units | Measured as | Source |
|---|
Results by group 0
Each measurement the trial posted, group by group, in the words and numbers it posted.
| Outcome | Group | Category | Value | Spread | Units | Source |
|---|
Participant flow 0
How many started, completed or left each group, period by period.
| Period | Milestone | Group | Participants | Units counted | Source |
|---|
Adverse events 0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
| Type | Event | Organ system | Group | Affected | At risk | Events | Source |
|---|
Adverse event totals 0
The totals the trial posted for each group.
| Total | Group | Affected | At risk | Source |
|---|
Papers 5
The papers the trial lists on ClinicalTrials.gov.
Grants 0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
| Project | Title | Principal investigators | Organization | Funder | Fiscal years | Source |
|---|
Trial comparisons 0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
| Comparison | Source |
|---|
Tests 4
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
| Test | Named as | Source |
|---|---|---|
| Stroop Color-Word Test | Primary outcome | ConductCognition |
| Trail Making Test A | Primary outcome | ConductCognition |
| Trail Making Test B | Primary outcome | ConductCognition |
| Verbal Learning | Primary outcome | ConductCognition |
Source 5
| Field | Value | Source |
|---|---|---|
| Release | trials-2026-11-12-0.4.0 | ClinicalTrials.gov |
| Release manifest SHA-256 | 0f4a8d8c48aee2a7573ae0fa94ecbeab70c1adbe449bbc95c424bc7d3e97b9d4 | ClinicalTrials.gov |
| Registry capture | 2026-11-12 | ClinicalTrials.gov |
| Results copy, AACT | 2026-03-23 | ClinicalTrials.gov |
| NIH clinical studies file | 2026-11-13 | ClinicalTrials.gov |
Release trials-2026-11-12-0.4.0
ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
NIH RePORTER's clinical studies and project files: Public domain (NIH RePORTER)