Trial · NCT06662383
A Study of Retatrutide (LY3437943) Compared to Tirzepatide (LY3298176) in Adults Who Have Obesity
NCT06662383, Phase 3, Active not recruiting, Eli Lilly and Company
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. A Study of Retatrutide (LY3437943) Compared to Tirzepatide (LY3298176) in Adults Who Have Obesity. Trials, record NCT06662383. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT06662383
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- A Study of Retatrutide (LY3437943) Compared to Tirzepatide (LY3298176) in Adults Who Have Obesity
- NCT number
- NCT06662383
- Status
- Active not recruiting
- Phases
- Phase 3
- Enrollment
- 800 participants, estimated
- Lead sponsor
- Eli Lilly and Company
- Conditions
- Obesity
- Interventions
- Retatrutide, Tirzepatide
- First posted
- 2024-10-28
- Last updated
- 2026-07-20
Source ClinicalTrials.gov
Registered outcomes10
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | Percent Change from Baseline in Body Weight | Baseline, Week 80 | |
| Secondary | Change from Baseline in Body Mass Index (BMI) | Baseline, Week 80 | |
| Secondary | Change from Baseline in Waist Circumference | Baseline, Week 80 | |
| Secondary | Percent Change from Baseline in Total Cholesterol | Baseline, Week 80 | |
| Secondary | Percent Change from Baseline in Triglycerides | Baseline, Week 80 | |
| Secondary | Change from Baseline in Systolic Blood Pressure (SBP) | Baseline, Week 80 | |
| Secondary | Change from Baseline in Diastolic Blood Pressure (DBP) | Baseline, Week 80 | |
| Secondary | Change from Baseline in Hemoglobin A1c (HbA1c) | Baseline, Week 80 | |
| Secondary | Percent Change from Baseline in Fasting Insulin | Baseline, Week 80 | |
| Secondary | Change from Baseline in Impact of Weight on Quality of Life-Lite Clinical Trials Version (IWQOL-Lite-CT) | Baseline, Week 80 |
Source ClinicalTrials.gov
Outcomes0
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
None in this release.
Results by group0
Each measurement the trial posted, group by group, in the words and numbers it posted.
None in this release.
Participant flow0
How many started, completed or left each group, period by period.
None in this release.
Adverse events0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
None in this release.
Adverse event totals0
The totals the trial posted for each group.
None in this release.
Papers0
The papers the trial lists on ClinicalTrials.gov.
None in this release.
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
None in this release.
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT06662383
GET https://conductscience.org/api/trials/v1/NCT06662383/registered