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Trial · NCT06663098

Atezolizumab and Rechallenge Chemotherapy in Relapsed Patients With Extensive-stage Small Cell Lung Cancer (ES-SCLC).

NCT06663098, Phase 2, Recruiting, Gruppo Oncologico Italiano di Ricerca Clinica

3 sourcestrials-2026-11-12-0.5.0

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ConductScience Library. Atezolizumab and Rechallenge Chemotherapy in Relapsed Patients With Extensive-stage Small Cell Lung Cancer (ES-SCLC). Trials, record NCT06663098. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT06663098

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Trial

As registered on ClinicalTrials.gov, in the graph's capture of the registry.

Title
Atezolizumab and Rechallenge Chemotherapy in Relapsed Patients With Extensive-stage Small Cell Lung Cancer (ES-SCLC).
NCT number
NCT06663098
Status
Recruiting
Phases
Phase 2
Enrollment
142 participants, estimated
Lead sponsor
Gruppo Oncologico Italiano di Ricerca Clinica
Conditions
Extensive Stage Small Cell Lung Cancer (ES-SCLC)
Interventions
Atezolizumab, Carboplatin, Etoposide
First posted
2024-10-29
Last updated
2025-03-13

Source ClinicalTrials.gov

Registered outcomes4

Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.

ListOutcomeTime frameDescription
Primaryoverall survivalthrough study completion, an average of 1 year
overall survival (OS), defined as the time from the date of registration to the date of death from any cause. Patients still alive at the time of analysis are censored at the last time they are known to be alive.
Secondaryfrequency of adverse events30 days post last dose of study drugToxicity will be assessed in the mITT population. Descriptive tables will be produced which provide the worst degree of toxicity measured over all cycles according to the NCI-CTCAE version 5.0
SecondaryProgression Free Survivalthrough study completion, an average of 6 months
Progression Free Survival (PFS) defined as the time from the patient registration to the evidence of progressive disease, or death, or the last date the patient was known to be progression-free and alive.
SecondaryObjective response ratethrough study completion, an average of 1 yearObjective response rate (ORR) is calculated as the sum of RECIST v1.1-defined CR and PR out of the number of assessable patients with measurable disease at baseline.

Outcomes0

Each outcome the trial posted results for, in ClinicalTrials.gov's words.

None in this release.

Results by group0

Each measurement the trial posted, group by group, in the words and numbers it posted.

None in this release.

Participant flow0

How many started, completed or left each group, period by period.

None in this release.

Adverse events0

Each adverse event the trial posted, group by group: the participants affected out of those at risk.

None in this release.

Adverse event totals0

The totals the trial posted for each group.

None in this release.

Papers12

The papers the trial lists on ClinicalTrials.gov.

PMIDListed asSource
23890065BACKGROUNDPubMed
24981975BACKGROUNDPubMed
30280641BACKGROUNDPubMed
31046803BACKGROUNDPubMed
31590988BACKGROUNDPubMed
31959349BACKGROUNDPubMed
32888454BACKGROUNDPubMed
32990939BACKGROUNDPubMed
33439693BACKGROUNDPubMed
33864941BACKGROUNDPubMed

1 to 10 of 12

See all 12 papers

Grants0

The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.

None in this release.

Trial comparisons0

Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.

None in this release.

Tests0

The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.

None in this release.

Data dates

The day each source was copied for this release.

ClinicalTrials.gov
2026-11-12
ClinicalTrials.gov
Results, from AACT
2026-03-23
AACT
NIH grant links
2026-11-13
NIH RePORTER

Sources 3

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ClinicalTrials.govNo license stated
  • NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ClinicalTrials.govnone stated
  • NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this trial from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/trials/v1/NCT06663098

GET https://conductscience.org/api/trials/v1/NCT06663098/registered