Trial · NCT06691386
Nicotine Pharmacokinetics and Subjective Effects of Oral Nicotine Products Relative to Smokeless Tobacco in Adult Users
NCT06691386, Not applicable, Completed, Altria Client Services LLC
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. Nicotine Pharmacokinetics and Subjective Effects of Oral Nicotine Products Relative to Smokeless Tobacco in Adult Users. Trials, record NCT06691386. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT06691386
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- Nicotine Pharmacokinetics and Subjective Effects of Oral Nicotine Products Relative to Smokeless Tobacco in Adult Users
- NCT number
- NCT06691386
- Status
- Completed
- Phases
- Not applicable
- Enrollment
- 64 participants, actual
- Lead sponsor
- Altria Client Services LLC
- Conditions
- Tobacco Use
- Interventions
- Test Product A, Test Product B, Test Product C, Test Product D, Test Product E, Reference Product F: Subjects' OBMST
- First posted
- 2024-11-15
- Last updated
- 2025-01-17
Source ClinicalTrials.gov
Registered outcomes3
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | Plasma Nicotine (ng/mL) | Day 1 through Day 6 | Maximum plasma nicotine concentration (Cmax) measured following the product use under controlled use conditions |
| Primary | Smokeless Urge and Craving Questionnaire | Day 1 through Day 6 | Maximum reduction in response relative to pre-use for subjective ratings of all items in the Smokeless Urge and Craving Questionnaire (Emax-UC) following the product use under controlled use conditions. Each question was paired with a 100 millimeter (mm) visual analog scale (VAS). The VAS was anchored with "Not at All" on the left and "Extremely on the right. Subjects placed a vertical line at a place along the VAS based on how he/she felt in the moment. Scoring of response based on measurement of distance in mm from "Not at All" hash to mark made by subject with no response being better or worse. |
| Primary | Product Effects Questionnaire | Day 1 through Day 6 | Maximum response for subjective ratings of all items in the Product Effects Questionnaire (Emax-PE) following the product use under controlled use conditions. Each question was paired with a 100 millimeter (mm) visual analog scale (VAS). The VAS was anchored with "Not at All" on the left and "Extremely" on the right. Subjects placed a vertical line at a place along the VAS based on how he/she felt in the moment. Scoring of response based on measurement of distance in mm from "Not at All" hash to mark made by subject with no response being better or worse. |
Source ClinicalTrials.gov
Outcomes0
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
None in this release.
Results by group0
Each measurement the trial posted, group by group, in the words and numbers it posted.
None in this release.
Participant flow0
How many started, completed or left each group, period by period.
None in this release.
Adverse events0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
None in this release.
Adverse event totals0
The totals the trial posted for each group.
None in this release.
Papers0
The papers the trial lists on ClinicalTrials.gov.
None in this release.
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
None in this release.
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT06691386
GET https://conductscience.org/api/trials/v1/NCT06691386/registered