The Effect of Caffeinated Chewing Gum on Cognitive Performance in Night-shift Emergency Physicians
NCT06693505, Not applicable, Completed, China Medical University Hospital
Trial 10
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
| Field | Value | Source |
|---|---|---|
| Title | The Effect of Caffeinated Chewing Gum on Cognitive Performance in Night-shift Emergency Physicians | ClinicalTrials.gov |
| NCT number | NCT06693505 | ClinicalTrials.gov |
| Status | Completed | ClinicalTrials.gov |
| Phases | Not applicable | ClinicalTrials.gov |
| Enrollment | 14 participants, actual | ClinicalTrials.gov |
| Lead sponsor | China Medical University Hospital | ClinicalTrials.gov |
| Conditions | Cognitive Performance, Sleep Quality | ClinicalTrials.gov |
| Interventions | caffeinated chewing gum, placebo | ClinicalTrials.gov |
| First posted | 2024-11-18 | ClinicalTrials.gov |
| Last updated | 2024-11-18 | ClinicalTrials.gov |
Registered outcomes 7
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description | Source |
|---|---|---|---|---|
| Primary | Corsi block test | baseline (preintervention), immediately after the intervention | There will be 9 purple squares in the screen, when the test starts, it will flash a number of them randomly in yellow color (the more the number increases), then you will hear "Go", then you have to click the order of the flashing ones, and then press "DONE" in the lower right corner. The smiley face means correct, the crying face means wrong. The maximum number of correct answers will be displayed at the end of the test, which is mainly to test the ability of situational awareness and working memory. The whole process takes about 2 minutes. | ClinicalTrials.gov |
| Primary | Task-switching paradigm | baseline (preintervention), immediately after the intervention | There are two shapes (circle, square) and two colors (yellow, blue), four combinations in total. At the beginning of the test, you will see "SHAPE" or "COLOR" (which means that the answer to the question will be based on the shape or color), and then a colorful pattern (e.g., yellow square or blue circle) will appear, then answer the question according to the answer you have just seen (shape or color) as soon as possible. Press B for circles, N for squares, B for yellow, N for blue, and finally the average reaction speed is displayed, which is a test of cognitive structure, flexibility, and plasticity in task processing. The whole test takes about 4 minutes. | ClinicalTrials.gov |
| Primary | Stroop Test | baseline (preintervention), immediately after the intervention | In this quiz, you will see different colors for different words, but all the answers are based on the colors (no matter what the words are). Press R for red, G for green, B for blue, and Y for yellow; for example, if you see "green in red color", you have to press R. The test results comprised a congruent condition, in which the key pressed corresponded correctly to the color on the screen, and an incongruent condition, in which the key pressed corresponded incorrectly to the color name on the screen. At the end of the test, the reaction time will be displayed, which is mainly a test of the ability to inhibit cognitive interference. The whole test takes about 5 minutes. | ClinicalTrials.gov |
| Primary | Visual search | baseline (preintervention), immediately after the intervention | In the visual search test, participants identified orange "T" s on the screen from upside-down orange "T" s, blue "T" s, and upside-down blue "T" s. When an orange "T" would appear, the participants were required to press the spacebar as quickly as possible. If no orange "T" appeared, the participants were required to not react. The test contains 80 search displays, each containing 5, 10, 15 and 20 items, mainly to test the search ability of dynamic vision. Reaction speed was displayed at the end of the test, and the whole test took about 4 minutes. | ClinicalTrials.gov |
| Primary | Wisconsin Card Sorting Task | baseline (preintervention), immediately after the intervention | There is a trial-and-error component to this test. You have to answer the questions first and then determine what the question is based on what is right or wrong. The test is presented in a matching mode, where a pattern on the left is matched with one of the four patterns on the right, and the matching criteria are color, shape, and number. During the test, the questions will be changed from time to time, so if you find out the rules and then suddenly get a question wrong, it means that the question has been changed. The number of errors is displayed at the end of the test to help measure a person's ability to reason abstractly and to change problem-solving strategies when necessary. The entire test lasted about 4 minutes. | ClinicalTrials.gov |
| Secondary | subjectively sleep quality | baseline (the sleep before intervention),the sleep after the intervention | subjectively by a single question score | ClinicalTrials.gov |
| Secondary | objectively sleep quality | baseline (the sleep before intervention),the sleep after the intervention | objectively by ActiGraph | ClinicalTrials.gov |
Outcomes 0
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
| Type | Outcome | Time frame | Population | Units | Measured as | Source |
|---|
Results by group 0
Each measurement the trial posted, group by group, in the words and numbers it posted.
| Outcome | Group | Category | Value | Spread | Units | Source |
|---|
Participant flow 0
How many started, completed or left each group, period by period.
| Period | Milestone | Group | Participants | Units counted | Source |
|---|
Adverse events 0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
| Type | Event | Organ system | Group | Affected | At risk | Events | Source |
|---|
Adverse event totals 0
The totals the trial posted for each group.
| Total | Group | Affected | At risk | Source |
|---|
Papers 0
The papers the trial lists on ClinicalTrials.gov.
| PMID | Listed as | Source |
|---|
Grants 0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
| Project | Title | Principal investigators | Organization | Funder | Fiscal years | Source |
|---|
Trial comparisons 0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
| Comparison | Source |
|---|
Tests 4
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
| Test | Named as | Source |
|---|---|---|
| Card Sorting Test (Berg) | Primary outcome | ConductCognition |
| Corsi Block-Tapping Test | Primary outcome | ConductCognition |
| Stroop Color-Word Test | Primary outcome | ConductCognition |
| Task Switching Test | Primary outcome | ConductCognition |
Source 5
| Field | Value | Source |
|---|---|---|
| Release | trials-2026-11-12-0.4.0 | ClinicalTrials.gov |
| Release manifest SHA-256 | 0f4a8d8c48aee2a7573ae0fa94ecbeab70c1adbe449bbc95c424bc7d3e97b9d4 | ClinicalTrials.gov |
| Registry capture | 2026-11-12 | ClinicalTrials.gov |
| Results copy, AACT | 2026-03-23 | ClinicalTrials.gov |
| NIH clinical studies file | 2026-11-13 | ClinicalTrials.gov |
Release trials-2026-11-12-0.4.0
ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
NIH RePORTER's clinical studies and project files: Public domain (NIH RePORTER)