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Trial · NCT06726395

Comparison of Cloxacillin and Benzylpenicillin in Penicillin Susceptible S. Aureus Bacteraemia

NCT06726395, Phase 4, Recruiting, Region Skane

3 sourcestrials-2026-11-12-0.5.0

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ConductScience Library. Comparison of Cloxacillin and Benzylpenicillin in Penicillin Susceptible S. Aureus Bacteraemia. Trials, record NCT06726395. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT06726395

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Trial

As registered on ClinicalTrials.gov, in the graph's capture of the registry.

Title
Comparison of Cloxacillin and Benzylpenicillin in Penicillin Susceptible S. Aureus Bacteraemia
NCT number
NCT06726395
Status
Recruiting
Phases
Phase 4
Enrollment
420 participants, estimated
Lead sponsor
Region Skane
Conditions
Staphylococcus Aureus Bacteraemia, Staphylococcal Bacteraemia, Staphylococcus Aureus Bloodstream Infections (BSI; Bacteremia), Staphylococcus (S.) Aureus Infection
Interventions
Penicillin G_1200mg, cloxacillin
First posted
2024-12-10
Last updated
2026-04-30

Source ClinicalTrials.gov

Registered outcomes8

Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.

ListOutcomeTime frameDescription
PrimarySurvival at 90 days without any treatment complicationsFrom enrollment to 90 days after end of treatmentComplications are defined as having any of; relapse within 90 days after treatment finish, need of change or addition of antibiotics due to side effects or treatment failure or adverse events.
SecondaryMortality at 90 daysFrom enrollment to 90 days after end of treatmentAll cause mortality within 90 days from enrollment
SecondaryRelapse 90 days after end of treatmentFrom enrollment to 90 days after end of treatmentRelapse with positive culturing from sterile sites or high suscpition of clinical relapse
SecondaryCumulative frequency of side effects within 90 daysFrom enrollment until 90 days.all side effects registered as a cumulative frequence
SecondaryCumulative frequence of change or addition of antibiotic treatment due to sideeffects or treatment failurefrom enrollment to end of treatment duration up to 90 daysEvery time additional antibiotics or change in antibiotic treatment is made due to either side effects or treatment failure (according to treating doctor)
SecondaryDecrease of Bacterial DNA in blood samplesFrom enrollment and first 5 daysBacterial DNA tested the first 5 days during study treatment.
OtherDays with intravenous antibioticsFrom enrollment and until end of treatmentDifferences between treatment groups
OtherDifferent outcome measures stratified by diagnosisFrom enrollment and up to 90 days after end of treatment90 days mortality, relapse 90 days after end of treatment, cumulative side effects stratified by diagnosis

Outcomes0

Each outcome the trial posted results for, in ClinicalTrials.gov's words.

None in this release.

Results by group0

Each measurement the trial posted, group by group, in the words and numbers it posted.

None in this release.

Participant flow0

How many started, completed or left each group, period by period.

None in this release.

Adverse events0

Each adverse event the trial posted, group by group: the participants affected out of those at risk.

None in this release.

Adverse event totals0

The totals the trial posted for each group.

None in this release.

Papers0

The papers the trial lists on ClinicalTrials.gov.

None in this release.

Grants0

The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.

None in this release.

Trial comparisons0

Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.

None in this release.

Tests0

The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.

None in this release.

Data dates

The day each source was copied for this release.

ClinicalTrials.gov
2026-11-12
ClinicalTrials.gov
Results, from AACT
2026-03-23
AACT
NIH grant links
2026-11-13
NIH RePORTER

Sources 3

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ClinicalTrials.govNo license stated
  • NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ClinicalTrials.govnone stated
  • NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this trial from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/trials/v1/NCT06726395

GET https://conductscience.org/api/trials/v1/NCT06726395/registered