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Trial · NCT06738394

Enhancing Physical Function in Older Adults With Chronic Kidney Disease

NCT06738394, Not applicable, Recruiting, Wake Forest University Health Sciences

3 sourcestrials-2026-11-12-0.5.0

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ConductScience Library. Enhancing Physical Function in Older Adults With Chronic Kidney Disease. Trials, record NCT06738394. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT06738394

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Trial

As registered on ClinicalTrials.gov, in the graph's capture of the registry.

Title
Enhancing Physical Function in Older Adults With Chronic Kidney Disease
NCT number
NCT06738394
Status
Recruiting
Phases
Not applicable
Enrollment
30 participants, estimated
Lead sponsor
Wake Forest University Health Sciences
Conditions
Chronic Kidney Diseases
Interventions
High-Velocity Resistance Training, Attention
First posted
2024-12-17
Last updated
2026-08-26

Source ClinicalTrials.gov

Registered outcomes20

Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.

ListOutcomeTime frameDescription
PrimaryNumber of Participants EnrolledMonth 6Number of participants enrolled with a goal of 30.
PrimaryPercent of Participant AdherenceWeek 13Percentage of exercise sessions attended for the HVRT group (out of 36 total exercise sessions)
PrimaryPercent of Participant RetentionWeek 13Percentage of participants retained at the final follow visit.
SecondaryChange in Short Physical Performance Battery (SPPB) ScoreFrom baseline to Follow-up (Week 13)
The short physical performance battery (SPPB) consists of three tests to assess lower extremity function: a balance test, a gait speed test, and a sit-to-stand test. Performance in each test will be assigned a score ranging from 0 to 4 points, and these scores will be summed to calculate the SPPB score out of 12. A higher SPPB score indicates better function, and scores of 10 or lower are indicative of high risk of disability.
SecondaryChange in Timed Up and Go Test durationFrom baseline to Follow-up (Week 13)For the timed up-and-go test, the time to complete this task will be measured in seconds. A lower number of seconds to complete the task is indicative of higher physical function.
SecondaryChange in lower body peak powerFrom baseline to Follow-up (Week 13)
Leg press peak power will be assessed at 5 relative intensities (40%, 50%, 60%, 70%, and 80% 1-repetition maximum). The highest peak power measurement among those 5 loads will be recorded as peak power. Greater peak power is indicative of greater lower body neuromuscular function.
OtherChange in Appendicular Lean MassFrom baseline to Follow-up (Week 13)Appendicular Lean Mass (kg/m\^2) will be measured via dual-energy X-ray absorptiometry (DXA). Higher appendicular lean mass is indicative of improved body composition.
OtherChange in isometric leg extension strengthFrom baseline to Follow-up (Week 13)
Isometric leg extension strength will be measured with a maximal isometric voluntary contraction of the dominant leg knee extensor muscles using a MicroFET2 hand-held dynamometer. Greater peak force is indicative of greater knee extensor strength.
OtherChange in lower body strengthFrom baseline to Follow-up (Week 13)
Lower body strength will be measured as the 1-repetition maximum on the leg press, which is the maximum load (kg) that can be moved 1 time only throughout the full range of motion. Increase in leg press 1-repetition maximum is indicative of improved lower body strength.
OtherChange in lower body muscle enduranceFrom baseline to Follow-up (Week 13)
Lower body muscle endurance will be measured on the leg press as the maximum number of repetitions completed at a load of 70% of baseline 1-repetition maximum with a fixed cadence of 60 bpm. An increase in the number of repetitions completed is indicative of an improvement in lower body muscle endurance.

Outcomes0

Each outcome the trial posted results for, in ClinicalTrials.gov's words.

None in this release.

Results by group0

Each measurement the trial posted, group by group, in the words and numbers it posted.

None in this release.

Participant flow0

How many started, completed or left each group, period by period.

None in this release.

Adverse events0

Each adverse event the trial posted, group by group: the participants affected out of those at risk.

None in this release.

Adverse event totals0

The totals the trial posted for each group.

None in this release.

Papers0

The papers the trial lists on ClinicalTrials.gov.

None in this release.

Grants0

The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.

None in this release.

Trial comparisons0

Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.

None in this release.

Tests1

The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.

TestNamed as
Stroop Color-Word TestOther outcome

Data dates

The day each source was copied for this release.

ClinicalTrials.gov
2026-11-12
ClinicalTrials.gov
Results, from AACT
2026-03-23
AACT
NIH grant links
2026-11-13
NIH RePORTER

Sources 3

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ClinicalTrials.govNo license stated
  • NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ClinicalTrials.govnone stated
  • NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this trial from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/trials/v1/NCT06738394

GET https://conductscience.org/api/trials/v1/NCT06738394/registered