Trial · NCT06738758
Multicenter Real-World Cohort Study Evaluating the Impact of Early Intensive Lipid-Lowering Therapy on the Prognosis of Acute Coronary Syndrome Patients(ELITE-ACS)
NCT06738758, Recruiting, Yun Dai Chen
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. Multicenter Real-World Cohort Study Evaluating the Impact of Early Intensive Lipid-Lowering Therapy on the Prognosis of Acute Coronary Syndrome Patients(ELITE-ACS). Trials, record NCT06738758. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT06738758
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- Multicenter Real-World Cohort Study Evaluating the Impact of Early Intensive Lipid-Lowering Therapy on the Prognosis of Acute Coronary Syndrome Patients(ELITE-ACS)
- NCT number
- NCT06738758
- Status
- Recruiting
- Enrollment
- 6,000 participants, estimated
- Lead sponsor
- Yun Dai Chen
- Conditions
- Acute Coronary Syndromes
- Interventions
- PCSK9 inhibitor, Statin+Ezetimibe/Hybutimibe compound, Statin
- First posted
- 2024-12-18
- Last updated
- 2025-03-17
Source ClinicalTrials.gov
Registered outcomes12
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | Lipid attainment rate at each visit node during the observation period (<1.4 mmol/L) | 3 days of medication; At hospital discharge, which is expected to occur between 5 to 10days after admission, depending on the patient's clinical progress; At 1, 3, 6, 12 months after discharge | Lipid attainment rate at each visit node during the observation period (\<1.4 mmol/L) |
| Secondary | The average time for different treatment groups to reach the guideline-recommended lipid standards (<1.4mmol/L) during the observation period. | 3 days of medication; At hospital discharge, which is expected to occur between 5 to 10days after admission, depending on the patient's clinical progress; At 1, 3, 6, 12 months after discharge | The average time for different treatment groups to reach the guideline-recommended lipid standards (\<1.4mmol/L) during the observation period. |
| Secondary | The overall incidence of the first major adverse cardiovascular events (MACEs) within 12 months in different treatment groups | 12 months | Description: MACEs was defined as the composite of myocardial infarction, ischemic stroke, cardiovascular death and coronary revascularization |
| Secondary | Time from in-hospital initiation of lipid-lowering therapy to first occurrence of any of the above clinical events | 12 months | |
| Secondary | Percentage change from baseline in LDL-C across treatment groups at different visit nodes | 3 days of medication; At hospital discharge, which is expected to occur between 5 to 10days after admission, depending on the patient's clinical progress; At 1, 3, 6, 12 months after discharge | |
| Secondary | Change from baseline in inflammatory factors | 3 days of medication; At hospital discharge, which is expected to occur between 5 to 10days after admission, depending on the patient's clinical progress; At 1, 3, 6, 12 months after discharge | Inflammatory factors include IL-6, CRP/Hypersensitive CRP |
| Other | The correlation between LDL-C in-hospital compliance, 1-month compliance, and 3-month compliance with MACE | At hospital discharge, which is expected to occur between 5 to 10days after admission, depending on the patient's clinical progress; At 1, 3, 6, 12 months after discharge | |
| Other | The correlation between the duration of LDL-C within the target and MACE | 12 months | |
| Other | The correlation between different baseline GRACE score levels (low, medium, high) and MACE | 12 months | |
| Other | The correlation between different baseline inflammatory cytokine level groups (quartiles) and MACE | 12 months |
1 to 10 of 12Source ClinicalTrials.gov
See all 12 registered outcomesOutcomes0
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
None in this release.
Results by group0
Each measurement the trial posted, group by group, in the words and numbers it posted.
None in this release.
Participant flow0
How many started, completed or left each group, period by period.
None in this release.
Adverse events0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
None in this release.
Adverse event totals0
The totals the trial posted for each group.
None in this release.
Papers1
The papers the trial lists on ClinicalTrials.gov.
| PMID | Listed as |
|---|---|
| 42137728 | DERIVED |
Source PubMed
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
None in this release.
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT06738758
GET https://conductscience.org/api/trials/v1/NCT06738758/registered