Trial · NCT06767358
Ketamine Sedation in the ICU (KANINE) RCT
NCT06767358, Phase 3, Recruiting, McMaster University
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. Ketamine Sedation in the ICU (KANINE) RCT. Trials, record NCT06767358. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT06767358
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- Ketamine Sedation in the ICU (KANINE) RCT
- NCT number
- NCT06767358
- Status
- Recruiting
- Phases
- Phase 3
- Enrollment
- 54 participants, estimated
- Lead sponsor
- McMaster University
- Conditions
- Mechanical Ventilation, Critically Ill Intensive Care Unit Patients
- Interventions
- ketamine hydrochloride, Normal saline placebo
- First posted
- 2025-01-09
- Last updated
- 2026-10-22
Source ClinicalTrials.gov
Registered outcomes19
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | Feasibility: Recruitment Rate | 3 months | Feasibility will be judged by the 3 outcomes of recruitment rate, consent rate, and protocol adherence. We define a successful recruitment rate of 0.5 patients per centre per month over the duration of the trial. |
| Primary | Feasibility: Consent Rate | 3 months | This will be judged by the 3 outcomes of recruitment rate, consent rate, and protocol adherence. We will define \>75% consent rate as successful. |
| Primary | Feasibility: Protocol Adherence | 3 months | This will be judged by the 3 outcomes of recruitment rate, consent rate, and protocol adherence. We will define ≥75% protocol adherence as successful. |
| Secondary | Ventilator-free Days at 28 days | 28 Days | |
| Secondary | 28-day mortality | 28 Days | |
| Secondary | ICU Mortality | 3 months | |
| Secondary | ICU Length of Stay | 3 months | |
| Secondary | Number of Participants receiving a Tracheostomy | 3 months | |
| Secondary | Hospital Mortality | 3 months | |
| Secondary | Hospital Length of Stay | 3 months |
1 to 10 of 19Source ClinicalTrials.gov
See all 19 registered outcomesOutcomes0
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
None in this release.
Results by group0
Each measurement the trial posted, group by group, in the words and numbers it posted.
None in this release.
Participant flow0
How many started, completed or left each group, period by period.
None in this release.
Adverse events0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
None in this release.
Adverse event totals0
The totals the trial posted for each group.
None in this release.
Papers0
The papers the trial lists on ClinicalTrials.gov.
None in this release.
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
None in this release.
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT06767358
GET https://conductscience.org/api/trials/v1/NCT06767358/registered