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Trial · NCT06817018

Ginger Root Extract for Sciatic Pain Individuals

NCT06817018, Phase 2, Recruiting, Leslie Shen

3 sourcestrials-2026-11-12-0.5.0

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ConductScience Library. Ginger Root Extract for Sciatic Pain Individuals. Trials, record NCT06817018. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT06817018

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Trial

As registered on ClinicalTrials.gov, in the graph's capture of the registry.

Title
Ginger Root Extract for Sciatic Pain Individuals
NCT number
NCT06817018
Status
Recruiting
Phases
Phase 2
Enrollment
80 participants, estimated
Lead sponsor
Leslie Shen
Conditions
Neuropathic Pain, Sciatic Pain
Interventions
Placebo, Ginger
First posted
2025-02-10
Last updated
2025-12-30

Source ClinicalTrials.gov

Registered outcomes8

Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.

ListOutcomeTime frameDescription
Primaryplasma lipopolysaccharide binding protein (LBP)baseline and after 8 weeksIntestinal permeability biomarker
Primaryfecal zonulinbaseline and after 8 weeksintestinal permeability marker
Primarybrief pain inventory (BPI)baseline and after 8 weekspain assessment
PrimarySF-MPQbaseline and after 8 weekspain assessment
Secondaryfecal metabolites using LC-MS/MS analysisbaseline and after 8 weeksUntargeted fecal metabolites will be assessed using LC-MS/MS analysis and the combination of retention time and mass signature provides great specificity for each metabolite identification.
Secondarygut microbiome using 16S rRNA amplicon sequencingbaseline and after 8 weeksFecal gut microbiome composition is a collection of microorganisms that live in the human digestive tract.
Secondaryneuroinflammation genesbaseline and after 8 weeksWhole blood neuroinflammation gene profiles will be analyzed using nCounter® Neuroinflammation Panel to evaluate pathways, processes, and cell types that are involved in neuroinflammation.
Secondarystructural connectivity using resting state-fMRIbaseline and after 8 weeks
Resting state-fMRI connectivity in brain will be examined between the left and right amygdala seed regions and the broader bilateral mPFC, defined using the probabilistic Harvard-Oxford Subcortical Structural Atlas in FSL.

Outcomes0

Each outcome the trial posted results for, in ClinicalTrials.gov's words.

None in this release.

Results by group0

Each measurement the trial posted, group by group, in the words and numbers it posted.

None in this release.

Participant flow0

How many started, completed or left each group, period by period.

None in this release.

Adverse events0

Each adverse event the trial posted, group by group: the participants affected out of those at risk.

None in this release.

Adverse event totals0

The totals the trial posted for each group.

None in this release.

Papers9

The papers the trial lists on ClinicalTrials.gov.

PMIDListed asSource
19356853BACKGROUNDPubMed
22861166BACKGROUNDPubMed
28429339BACKGROUNDPubMed
29369967BACKGROUNDPubMed
32490042BACKGROUNDPubMed
34748918BACKGROUNDPubMed
35047525BACKGROUNDPubMed
35873544BACKGROUNDPubMed
41831719DERIVEDPubMed

Grants0

The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.

None in this release.

Trial comparisons0

Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.

None in this release.

Tests0

The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.

None in this release.

Data dates

The day each source was copied for this release.

ClinicalTrials.gov
2026-11-12
ClinicalTrials.gov
Results, from AACT
2026-03-23
AACT
NIH grant links
2026-11-13
NIH RePORTER

Sources 3

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ClinicalTrials.govNo license stated
  • NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ClinicalTrials.govnone stated
  • NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this trial from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/trials/v1/NCT06817018

GET https://conductscience.org/api/trials/v1/NCT06817018/registered