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Trial · NCT06831175

Phase II Study of PD-1 Inhibitor Combined With Apatinib and Mitotane in the Treatment of Advanced Adrenal Cortical Carcinoma

NCT06831175, Phase 2, Recruiting, West China Hospital

3 sourcestrials-2026-11-12-0.4.0

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ConductScience Library. Phase II Study of PD-1 Inhibitor Combined With Apatinib and Mitotane in the Treatment of Advanced Adrenal Cortical Carcinoma. Trials, record NCT06831175. Release trials-2026-11-12-0.4.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT06831175

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Trial

As registered on ClinicalTrials.gov, in the graph's capture of the registry.

Title
Phase II Study of PD-1 Inhibitor Combined With Apatinib and Mitotane in the Treatment of Advanced Adrenal Cortical Carcinoma
NCT number
NCT06831175
Status
Recruiting
Phases
Phase 2
Enrollment
28 participants, estimated
Lead sponsor
West China Hospital
Conditions
Adrenal Cortical Carcinoma, Adrenal Cortical Cancer, Adrenal Cancer
Interventions
Camrelizumab, Apatinib, mitotane
First posted
2025-02-17
Last updated
2025-06-03

Source ClinicalTrials.gov

Registered outcomes4

Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.

ListOutcomeTime frameDescription
Primaryobjective response rateup to 24 monthsThe rate of complete response and partial response.
Secondarydisease-free survivalup to 60 monthsThe time from the administration of the first dose to first disease progression or death.
Secondaryprogression-free survivalup to 60 monthsThe time from the commencement of therapy to the first evidence of disease progression or death.
Secondaryincidence of adverse eventsup to 60 monthsGraded by National Cancer Institute (NCI) Common Terminology Criteria for Adverse Events (CTCAE) version 4.0.

Outcomes0

Each outcome the trial posted results for, in ClinicalTrials.gov's words.

None in this release.

Results by group0

Each measurement the trial posted, group by group, in the words and numbers it posted.

None in this release.

Participant flow0

How many started, completed or left each group, period by period.

None in this release.

Adverse events0

Each adverse event the trial posted, group by group: the participants affected out of those at risk.

None in this release.

Adverse event totals0

The totals the trial posted for each group.

None in this release.

Papers10

The papers the trial lists on ClinicalTrials.gov.

PMIDListed asSource
11572030BACKGROUNDPubMed
16172198BACKGROUNDPubMed
16551738BACKGROUNDPubMed
16670169BACKGROUNDPubMed
22551107BACKGROUNDPubMed
24423978BACKGROUNDPubMed
29967789BACKGROUNDPubMed
31533818BACKGROUNDPubMed
31644329BACKGROUNDPubMed
39609453BACKGROUNDPubMed

Grants0

The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.

None in this release.

Trial comparisons0

Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.

None in this release.

Tests0

The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.

None in this release.

Source

Release
trials-2026-11-12-0.4.0
Release manifest SHA-256
0f4a8d8c48aee2a7573ae0fa94ecbeab70c1adbe449bbc95c424bc7d3e97b9d4
Registry capture
2026-11-12
Results copy, AACT
2026-03-23
NIH clinical studies file
2026-11-13

Source ClinicalTrials.gov

Sources 3

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ClinicalTrials.govNone stated
  • NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ClinicalTrials.govnone stated
  • NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this trial from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/trials/v1/NCT06831175

GET https://conductscience.org/api/trials/v1/NCT06831175/registered