Trial · NCT06852209
Registered outcomes17
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
1 to 17 of 17
Download this page as JSON| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | Differential CEN-DMN activity and imaging contrast between regulation and rest | Through study training completion, an average of 4 weeks | Change from baseline to each training session on the CEN-DMN activity during regulation compared with rest, in the experimental and control groups |
| Secondary | Evolution of global cognition assessed by the Montreal Cognitive Assessment (MoCA) | Through study completion, an average of 6 weeks | Change from baseline to the end of the study on the MoCA score. The MoCA score allows the detection of mild cognitive impairment and is ranged from 0 (minimum) to 30 (maximum : no cognitive impairment). |
| Secondary | Evolution of executive functions assessed by a composite score | through study completion, an average of 6 weeks | Change from baseline to the end of the study on a composite Z-score made from the averages of the Z-scores of the following tests : * verbal fluency : the subject is asked to cite a maximum of animals, letters starting with the letter P and V in 60 seconds) ; * memory span (working memory) : the subject is asked to restitute a maximum of the items of a list immediatly after hearing them) ; * Trail making Test (cognitive flexibility) : the subject is asked to link a set of digits in increasing order, alternating with letters, or items of different shapes or colors, the number of errors is recorded ; * Stroop task (inhibition capacity) : the subject is asked to name the font color of a list of words of colors which don't match their font color ; * Zoo testing plan (scheduling ability) : the subject is asked to follow a list of instructions for the visit of a zoo, while dealing with a list of constraints. |
| Secondary | Evolution of attentional functions assessed by the Mesulam cancellation task | Through study completion, an average of 6weeks | Change from baseline to the end of the study on the Mesulam cancellation task : the subject is asked to cancel a specific target among random arrays of structured and unstructured verbal and nonverbal stimuli. |
| Secondary | Evolution of processing speed assessed by the Symbol Digit Modalities Test (SDMT) | Through study completion, an average of 6 weeks | Change from baseline to the end of the study on the SDMT : the subject is provided with a set of symbols corresponding to numbers, and he is asked to write the symbols corresponding to a specific list of numbers in 5 minutes. |
| Secondary | Evolution of memory functions assessed by the 16-item Free and Cued Recall | Through study completion, an average of 6 weeks | Change from baseline to the end of the study on the 16-item Free and Cued Recall : the subject is asked to recall a set of 16 words presented by 4, immediately and after an interfering task, the number of free and cued correct recalls are recorded. |
| Secondary | Evolution of visuospatial functions assessed by the Rey figure | Through study completion, an average of 6 weeks | Change from baseline to the end of the study on the Rey figure : the subject is asked to copy a complex figure as quickly as possible, and then, to reproduce the figure without the model. |
| Secondary | Evolution of language functions assessed byt the 40-item neuropsychological semantic battery | Through study completion, an average of 6 weeks | Change from baseline to the end of the study on the 40-item neuropsychological semantic battery : the subject is asked to name a set of 40 living and non living items in verbal and visual conditions, across 6 subtests of matching. |
| Secondary | Evolution of the Central Executive Network (CEN) activity | Through study training completion, an average of 4 weeks | Change from baseline to each training session in the CEN activity recorded in the CEN mask during regulation compared with rest, in the experimental and control groups. The CEN mask is a binary mask individualized after running a pipeline for each subject, and the functional activity into this mask is extracted to assess the specific trajectory of the CEN activity. |
| Secondary | Evolution of the Default Mode Network (DMN) activity | Through study training completion, an average of 4 weeks | Change from baseline to each training session in the DMN activity recorded in the DMN mask during regulation compared with rest, in the experimental and control groups. The DMN mask is a binary mask individualized after running a pipeline for each subject, and the functional activity into this mask is extracted to assess the specific trajectory of DMN activity. |
| Secondary | Evolution of activity in the whole brain | Through study training completion, an average of 4 weeks | Change from baseline to each training session on the whole brain activity during regulation compared with rest, in the experimental and control groups |
| Secondary | Evolution of resting state CEN and DMN activity | Through study completion, an average of 6 weeks | Change in correlation between resting state CEN and DMN activity before intervention compared with after intervention. |
| Secondary | Microstructural changes assessed by Fractional Anisotropy (FA) | Through study completion, an average of 6 weeks | Change in median FA parameters before intervention compared with after intervention |
| Secondary | Microstructural changes assessed by Mean Diffusivity (MD) | Through study completion, an average of 6 weeks | Change in median MD parameters (mm2/sec) before intervention compared with after intervention |
| Secondary | Microstructural changes assessed by Axial Diffusivity (AD) | Through study completion, an average of 6 weeks | Change in median AD parameters (mm2/sec) before intervention compared with after intervention |
| Secondary | Microstructural changes assessed by Radial Diffusivity (RD) | Through study completion, an average of 6 weeks | Change in median RD parameters (mm2/sec) before intervention compared with after intervention |
| Secondary | Differential CEN-DMN activity and imaging contrast between regulation and rest, without neurofeedback | Through study completion, an average of 6 weeks | Change from baseline to the last fMRI session (" transfert session " without neurofeedback) on the CEN-DMN activity during regulation compared with rest, in the experimental and control groups |
Source ClinicalTrials.govtrials-2026-11-12-0.5.0
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this list from software.
Twenty rows a page, as JSON. No key.
GET https://conductscience.org/api/trials/v1/NCT06852209/registered