Trial · NCT06907121
Investigation of Growth Hormone and Platelet-Rich Plasma on Joint Health
NCT06907121, Phase 2, Phase 3, Not yet recruiting, Integrant Pty Ltd
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. Investigation of Growth Hormone and Platelet-Rich Plasma on Joint Health. Trials, record NCT06907121. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT06907121
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- Investigation of Growth Hormone and Platelet-Rich Plasma on Joint Health
- NCT number
- NCT06907121
- Status
- Not yet recruiting
- Phases
- Phase 2, Phase 3
- Enrollment
- 192 participants, estimated
- Lead sponsor
- Integrant Pty Ltd
- Conditions
- Arthritis Ankle, Arthritis Knee
- Interventions
- Intra-Articular Injection of Growth Hormone and Platelet-Rich Plasma, Saline (NaCl 0,9 %) (placebo)
- First posted
- 2025-04-02
- Last updated
- 2026-08-26
Source ClinicalTrials.gov
Registered outcomes4
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | Ankle mobility and functionality test with FAOS scale | Baseline, 6-months after final injection | The Foot and Ankle Outcome Score (FAOS) scale is a widely used outcome measure for ankle and hindfoot conditions, including ankle arthritis, assessing pain, function, and alignment, with scores ranging from 0 to 100, where higher scores indicate better function. |
| Primary | Knee mobility and functionality test with WOMAC scale | Baseline, 6-months after final injection | The Western Ontario and McMaster Universities Arthritic Index (WOMAC) is a validated self-administered health status measure used in assessing pain, stiffness, and function in patients with arthritic knee. The WOMAC measures five items for pain (score range 0-20), two for stiffness (score range 0-8), and 17 for functional limitation, with the score range being 0-68. A higher score indicates worse symptons. |
| Secondary | MRI Imaging of the affected arthritic joint | Baseline, 6-months after final injection | The MRI scans will be evaluated by a radiologist blinded to the treatment allocation to assess changes in: Cartilage volume and thickness, Synovial inflammation (e.g., synovitis), Bone marrow edema, Osteophyte formation, Other structural changes relevant to arthritis progression |
| Secondary | Blood test for hormone | Baseline, 2 hours after each injection | Blood tests to check for growth hormone within the blood system. |
Source ClinicalTrials.gov
Outcomes0
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
None in this release.
Results by group0
Each measurement the trial posted, group by group, in the words and numbers it posted.
None in this release.
Participant flow0
How many started, completed or left each group, period by period.
None in this release.
Adverse events0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
None in this release.
Adverse event totals0
The totals the trial posted for each group.
None in this release.
Papers0
The papers the trial lists on ClinicalTrials.gov.
None in this release.
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
None in this release.
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT06907121
GET https://conductscience.org/api/trials/v1/NCT06907121/registered