Trial · NCT06919354
A Study of GNTI-122 in Adults Recently Diagnosed With T1D
NCT06919354, Phase 1, Recruiting, GentiBio, Inc
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. A Study of GNTI-122 in Adults Recently Diagnosed With T1D. Trials, record NCT06919354. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT06919354
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- A Study of GNTI-122 in Adults Recently Diagnosed With T1D
- NCT number
- NCT06919354
- Status
- Recruiting
- Phases
- Phase 1
- Enrollment
- 16 participants, estimated
- Lead sponsor
- GentiBio, Inc
- Conditions
- Type 1 Diabetes (T1D), Type 1 Diabetes Mellitus
- Interventions
- GNTI-122
- First posted
- 2025-04-09
- Last updated
- 2026-10-20
Source ClinicalTrials.gov
Registered outcomes4
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | Safety and tolerability of GNTI-122 with and without rapamycin in adult participants with recently diagnosed T1D | Week 78 | Cumulative AEs/SAEs and clinically significant abnormalities in physical exams, vital signs, clinical laboratory measures, and other clinical assessments |
| Secondary | Cellular kinetics of GNTI-122 with and without rapamycin in adult participants with recently diagnosed T1D | Week 78 | Measurement of maximum concentration of circulating engineered regulatory T cells as measured by droplet digital polymerase chain reaction |
| Secondary | Cellular kinetics of GNTI-122 with and without rapamycin in adult participants with recently diagnosed T1D | Week 78 | Measurement of area under the concentration-time curve \[AUC\] of circulating engineered regulatory T cells |
| Secondary | Cellular kinetics of GNTI-122 with and without rapamycin in adult participants with recently diagnosed T1D | Week 78 | Measurement of half-life of circulating engineered regulatory T cells |
Source ClinicalTrials.gov
Outcomes0
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
None in this release.
Results by group0
Each measurement the trial posted, group by group, in the words and numbers it posted.
None in this release.
Participant flow0
How many started, completed or left each group, period by period.
None in this release.
Adverse events0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
None in this release.
Adverse event totals0
The totals the trial posted for each group.
None in this release.
Papers0
The papers the trial lists on ClinicalTrials.gov.
None in this release.
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
None in this release.
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT06919354
GET https://conductscience.org/api/trials/v1/NCT06919354/registered