Trial · NCT06922240
Riociguat-Discontinue Effects on Right HEART in CTEPH (RED-HEART)
NCT06922240, Phase 3, Recruiting, Suqiao Yang
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. Riociguat-Discontinue Effects on Right HEART in CTEPH (RED-HEART). Trials, record NCT06922240. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT06922240
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- Riociguat-Discontinue Effects on Right HEART in CTEPH (RED-HEART)
- NCT number
- NCT06922240
- Status
- Recruiting
- Phases
- Phase 3
- Enrollment
- 68 participants, estimated
- Lead sponsor
- Suqiao Yang
- Conditions
- Chronic Thromboembolic Pulmonary Hypertension
- Interventions
- Riociguat, Routine Treatment
- First posted
- 2025-04-10
- Last updated
- 2025-04-30
Source ClinicalTrials.gov
Registered outcomes6
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | Change from Baseline in the Cardiac Output at 6 Months. | Baseline and 6-month follow-up | Cardiac Output was measured by right heart catheterization. |
| Secondary | Change from Baseline in the Pulmonary Vascular Resistance at 6 Months. | Baseline and 6-month follow-up | Pulmonary Vascular Resistance was measured by right heart catheterization. |
| Secondary | Change from Baseline in the concentration of NT-proBNP at 6 Months. | Baseline and 6-month follow-up | The concentration of NTproBNP in serum was detected in pg/ml |
| Secondary | Change from Baseline in the 6-minute walking distance at 6 Months. | Baseline, 3-month follow-up, and 6-month follow-up | 6-minute walking distance was measured by 6-minute walking test |
| Secondary | All-cause mortality | From the baseline to the completion follow-up,an average of 6 months | Observe and record All-cause mortality |
| Secondary | Combined incidence of all-cause death, re-hospitalization or disability/incapacity events due to clinical exacerbation of pulmonary hypertension | From the baseline to the completion follow-up,an average of 6 months | Observe and record All-cause mortality, clinical exacerbation of pulmonary hypertension leading to re-hospitalization or disability/incapacity |
Source ClinicalTrials.gov
Outcomes0
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
None in this release.
Results by group0
Each measurement the trial posted, group by group, in the words and numbers it posted.
None in this release.
Participant flow0
How many started, completed or left each group, period by period.
None in this release.
Adverse events0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
None in this release.
Adverse event totals0
The totals the trial posted for each group.
None in this release.
Papers0
The papers the trial lists on ClinicalTrials.gov.
None in this release.
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
None in this release.
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT06922240
GET https://conductscience.org/api/trials/v1/NCT06922240/registered